Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014279..2014550 Replicon chromosome
Accession NZ_CP053604
Organism Escherichia coli strain NEB10-beta

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014317..2014420 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014279..2014550 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO394_RS09885 2011436..2012875 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HO394_RS09890 2012993..2013229 + 237 WP_001295499.1 DUF1480 family protein -
HO394_RS09895 2013334..2013525 + 192 WP_000457842.1 YebW family protein -
HO394_RS09900 2013526..2014182 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2014279..2014550 + 272 - - Antitoxin
- 2014317..2014420 - 104 - - Toxin
HO394_RS09905 2014578..2014919 - 342 WP_000976476.1 YebY family protein -
HO394_RS09910 2014932..2015804 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HO394_RS09915 2015808..2016182 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HO394_RS09920 2016321..2016551 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HO394_RS09925 2016653..2017309 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HO394_RS09930 2017333..2017995 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T157103 NZ_CP053604:c2014420-2014317 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT157103 NZ_CP053604:2014279-2014550 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References