Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1908460..1908731 Replicon chromosome
Accession NZ_CP053603
Organism Escherichia coli strain Dam/Dcm

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1908498..1908601 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1908460..1908731 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO395_RS09305 1905617..1907056 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HO395_RS09310 1907174..1907410 + 237 WP_001295499.1 DUF1480 family protein -
HO395_RS09315 1907515..1907706 + 192 WP_000457842.1 YebW family protein -
HO395_RS09320 1907707..1908363 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1908460..1908731 + 272 - - Antitoxin
- 1908498..1908601 - 104 - - Toxin
HO395_RS09325 1908759..1909100 - 342 WP_000976476.1 YebY family protein -
HO395_RS09330 1909113..1909985 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HO395_RS09335 1909989..1910363 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HO395_RS09340 1910502..1910732 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HO395_RS09345 1910834..1911490 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HO395_RS09350 1911514..1912176 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T157066 NZ_CP053603:c1908601-1908498 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT157066 NZ_CP053603:1908460-1908731 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References