Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2566284..2566555 Replicon chromosome
Accession NZ_CP053599
Organism Escherichia coli strain NEBExpress

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2566414..2566517 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2566284..2566555 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO399_RS12075 2562840..2563502 - 663 WP_000944245.1 exodeoxyribonuclease X -
HO399_RS12080 2563526..2564182 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
HO399_RS12085 2564284..2564514 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HO399_RS12090 2564653..2565027 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HO399_RS12095 2565031..2565903 + 873 WP_000879293.1 copper homeostasis membrane protein CopD -
HO399_RS12100 2565916..2566257 + 342 WP_000976472.1 YebY family protein -
- 2566284..2566555 - 272 - - Antitoxin
- 2566414..2566517 + 104 - - Toxin
HO399_RS12105 2566652..2567308 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HO399_RS12110 2567309..2567500 - 192 WP_001296140.1 YebW family protein -
HO399_RS12115 2567605..2567841 - 237 WP_001295499.1 DUF1480 family protein -
HO399_RS12120 2567959..2569398 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T156956 NZ_CP053599:2566414-2566517 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT156956 NZ_CP053599:c2566555-2566284 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References