Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2566255..2566526 Replicon chromosome
Accession NZ_CP053592
Organism Escherichia coli strain NEBExpress_Iq

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2566385..2566488 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2566255..2566526 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO403_RS12085 2562811..2563473 - 663 WP_000944245.1 exodeoxyribonuclease X -
HO403_RS12090 2563497..2564153 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
HO403_RS12095 2564255..2564485 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HO403_RS12100 2564624..2564998 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HO403_RS12105 2565002..2565874 + 873 WP_000879293.1 copper homeostasis membrane protein CopD -
HO403_RS12110 2565887..2566228 + 342 WP_000976472.1 YebY family protein -
- 2566255..2566526 - 272 - - Antitoxin
- 2566385..2566488 + 104 - - Toxin
HO403_RS12115 2566623..2567279 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HO403_RS12120 2567280..2567471 - 192 WP_001296140.1 YebW family protein -
HO403_RS12125 2567576..2567812 - 237 WP_001295499.1 DUF1480 family protein -
HO403_RS12130 2567930..2569369 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T156896 NZ_CP053592:2566385-2566488 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT156896 NZ_CP053592:c2566526-2566255 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References