Detailed information of TA system TA156888

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prpT-prpA/ParE-CC2985
• Location: 105206..105755
• Replicon: plasmid unnamed
• Accession: NZ_CP053580
• Organism: Salmonella enterica strain 94-0093

Toxin (Protein)

• Gene name: PrpT
• Uniprot ID: -
• Locus tag: HPG92_RS00510
• Protein ID: WP_171774032.1
• Coordinates: 105459..105755 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: PrpA
• Uniprot ID: -
• Locus tag: HPG92_RS00505
• Protein ID: WP_171774031.1
• Coordinates: 105206..105472 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HPG92_RS00475	100517..101068	+	552	WP_171774026.1	fimbrial protein	-
HPG92_RS00480	101083..101628	+	546	WP_171774027.1	fimbrial protein	-
HPG92_RS00485	101873..102226	+	354	WP_171774028.1	LuxR C-terminal-related transcriptional regulator	-
HPG92_RS00490	102277..102486	+	210	WP_171774029.1	faeA-like family protein	-
HPG92_RS00495	102857..103067	+	211	Protein_98	GNAT family N-acetyltransferase	-
HPG92_RS00500	103265..104662	+	1398	WP_171774030.1	ISNCY family transposase	-
HPG92_RS00505	105206..105472	+	267	WP_171774031.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
HPG92_RS00510	105459..105755	+	297	WP_171774032.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HPG92_RS00515	106052..106783	+	732	Protein_102	site-specific integrase	-
HPG92_RS00520	107087..108079	-	993	WP_077907168.1	RepB family plasmid replication initiator protein	-
HPG92_RS00525	108933..109202	+	270	WP_171774033.1	DUF1778 domain-containing protein	-
HPG92_RS00530	109206..109736	+	531	WP_171774034.1	GNAT family N-acetyltransferase	-
HPG92_RS00535	109782..109968	+	187	Protein_106	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..124247	124247

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-119)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-46)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 12707.25 Da
• Isoelectric Point: 12.7912

>T156888 WP_171774032.1 NZ_CP053580:105459-105755 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 297 bp

>T156888 NZ_CP069072:c3136070-3135678 [Mycobacterium tuberculosis]
ATGACGACGGTGCTGCTCGACTCGCATGTGGCCTACTGGTGGTCGGCCGAGCCGCAGCGTCTCAGCATGGCGGCGAGCCA
GGCCATCGAACACGCCGACGAGCTCGCCGTCGCCGCGATTTCGTGGTTCGAGCTGGCTTGGCTTGCCGAACAGGAACGCA
TCCAACTGGCGATTCCGGTGCTGTCCTGGCTTCAGCAGCTGGCCGAGCACGTTCGCACCGTCGGTATCACGCCCTCGGTC
GCCGCCACGGCGGTGGCGCTGCCCTCGTCGTTCCCCGGCGATCCGGCCGACCGGTTGATCTACGCCACCGCGATCGAACA
CGGCTGGCGGCTGGTGACCAAGGACCGGCGGCTACGCAGTCATCGGCACCCACGACCGGTCACCGTCTGGTAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 11425.51 Da
• Isoelectric Point: 12.7445

>AT156888 WP_171774031.1 NZ_CP053580:105206-105472 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKK

Nucleotide

• Length: 267 bp

>AT156888 NZ_CP069072:c3136282-3136067 [Mycobacterium tuberculosis]
ATGACCGCTACGGAGGTGAAGGCGAAGATCCTCTCCTTGCTTGATGAAGTGGCCCAGGGCGAGGAGATCGAGATCACCAA
ACACGGCCGCACCGTGGCCCGGCTGGTGGCAGCGACGGGGCCGCACGCGCTGAAGGGTCGATTCTCGGGTGTGGCGATGG
CGGCCGTGGATGACGACGAACTCTTCACCACCGGGGTTTCGTGGAACGTTTCATGA