Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prpT-prpA/ParE-CC2985
Location 105206..105755 Replicon plasmid unnamed
Accession NZ_CP053580
Organism Salmonella enterica strain 94-0093

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag HPG92_RS00510 Protein ID WP_171774032.1
Coordinates 105459..105755 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID -
Locus tag HPG92_RS00505 Protein ID WP_171774031.1
Coordinates 105206..105472 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPG92_RS00475 100517..101068 + 552 WP_171774026.1 fimbrial protein -
HPG92_RS00480 101083..101628 + 546 WP_171774027.1 fimbrial protein -
HPG92_RS00485 101873..102226 + 354 WP_171774028.1 LuxR C-terminal-related transcriptional regulator -
HPG92_RS00490 102277..102486 + 210 WP_171774029.1 faeA-like family protein -
HPG92_RS00495 102857..103067 + 211 Protein_98 GNAT family N-acetyltransferase -
HPG92_RS00500 103265..104662 + 1398 WP_171774030.1 ISNCY family transposase -
HPG92_RS00505 105206..105472 + 267 WP_171774031.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HPG92_RS00510 105459..105755 + 297 WP_171774032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HPG92_RS00515 106052..106783 + 732 Protein_102 site-specific integrase -
HPG92_RS00520 107087..108079 - 993 WP_077907168.1 RepB family plasmid replication initiator protein -
HPG92_RS00525 108933..109202 + 270 WP_171774033.1 DUF1778 domain-containing protein -
HPG92_RS00530 109206..109736 + 531 WP_171774034.1 GNAT family N-acetyltransferase -
HPG92_RS00535 109782..109968 + 187 Protein_106 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..124247 124247


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-119)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 12707.25 Da        Isoelectric Point: 12.7912

>T156888 WP_171774032.1 NZ_CP053580:105459-105755 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKK

Download         Length: 297 bp

>T156888 NZ_CP069072:c3136070-3135678 [Mycobacterium tuberculosis]
ATGACGACGGTGCTGCTCGACTCGCATGTGGCCTACTGGTGGTCGGCCGAGCCGCAGCGTCTCAGCATGGCGGCGAGCCA
GGCCATCGAACACGCCGACGAGCTCGCCGTCGCCGCGATTTCGTGGTTCGAGCTGGCTTGGCTTGCCGAACAGGAACGCA
TCCAACTGGCGATTCCGGTGCTGTCCTGGCTTCAGCAGCTGGCCGAGCACGTTCGCACCGTCGGTATCACGCCCTCGGTC
GCCGCCACGGCGGTGGCGCTGCCCTCGTCGTTCCCCGGCGATCCGGCCGACCGGTTGATCTACGCCACCGCGATCGAACA
CGGCTGGCGGCTGGTGACCAAGGACCGGCGGCTACGCAGTCATCGGCACCCACGACCGGTCACCGTCTGGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 11425.51 Da        Isoelectric Point: 12.7445

>AT156888 WP_171774031.1 NZ_CP053580:105206-105472 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKK

Download         Length: 267 bp

>AT156888 NZ_CP069072:c3136282-3136067 [Mycobacterium tuberculosis]
ATGACCGCTACGGAGGTGAAGGCGAAGATCCTCTCCTTGCTTGATGAAGTGGCCCAGGGCGAGGAGATCGAGATCACCAA
ACACGGCCGCACCGTGGCCCGGCTGGTGGCAGCGACGGGGCCGCACGCGCTGAAGGGTCGATTCTCGGGTGTGGCGATGG
CGGCCGTGGATGACGACGAACTCTTCACCACCGGGGTTTCGTGGAACGTTTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References