Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1952720..1952860 Replicon chromosome
Accession NZ_CP053572
Organism Serratia marcescens strain S7.1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1952764..1952860 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1952720..1952860 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0335_RS09275 1947920..1948345 + 426 WP_107226957.1 RNA polymerase-binding protein DksA -
F0335_RS09280 1948540..1949493 + 954 WP_063990329.1 prolyl aminopeptidase -
F0335_RS09285 1949527..1949757 - 231 WP_149559950.1 DNA polymerase III subunit theta -
F0335_RS09290 1950102..1950620 + 519 WP_025302449.1 non-heme ferritin -
F0335_RS09295 1950945..1951328 + 384 WP_004940886.1 CopC domain-containing protein YobA -
F0335_RS09300 1951331..1952212 + 882 WP_063989547.1 copper homeostasis membrane protein CopD -
F0335_RS09305 1952282..1952622 + 341 Protein_1791 YebY family protein -
- 1952720..1952860 - 141 - - Antitoxin
- 1952764..1952860 + 97 - - Toxin
F0335_RS09310 1952939..1953295 - 357 WP_149559953.1 integrase -
F0335_RS09315 1953342..1953941 + 600 WP_149559949.1 hypothetical protein -
F0335_RS09320 1953932..1954240 + 309 WP_149559948.1 hypothetical protein -
F0335_RS09325 1954355..1955365 + 1011 WP_149559947.1 P63C domain-containing protein -
F0335_RS09330 1955643..1956086 - 444 WP_175089902.1 hypothetical protein -
F0335_RS09335 1956258..1956458 + 201 WP_149559945.1 hypothetical protein -
F0335_RS09340 1956463..1956843 + 381 Protein_1798 lysozyme -
F0335_RS09345 1957120..1957773 - 654 WP_149559944.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1946828..1956873 10045


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T156858 NZ_CP053572:1952764-1952860 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT156858 NZ_CP053572:c1952860-1952720 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGTCTACCACGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References