Detailed information of TA system TA156822

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 1150948..1151504
• Replicon: chromosome
• Accession: NZ_CP053541
• Organism: Vibrio europaeus strain NPI-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: HOO69_RS05210
• Protein ID: WP_171801475.1
• Coordinates: 1150948..1151253 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: HOO69_RS05215
• Protein ID: WP_171801476.1
• Coordinates: 1151262..1151504 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HOO69_RS05180	1146171..1146536	-	366	WP_069666187.1	CidA/LrgA family protein	-
HOO69_RS05185	1146682..1148106	-	1425	WP_171801470.1	exodeoxyribonuclease I	-
HOO69_RS05190	1148603..1148848	+	246	WP_171801471.1	hypothetical protein	-
HOO69_RS05195	1148935..1149609	+	675	WP_171801472.1	hypothetical protein	-
HOO69_RS05200	1149853..1150404	+	552	WP_171801473.1	VRR-NUC domain-containing protein	-
HOO69_RS05205	1150526..1150894	+	369	WP_171801474.1	hypothetical protein	-
HOO69_RS05210	1150948..1151253	-	306	WP_171801475.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HOO69_RS05215	1151262..1151504	-	243	WP_171801476.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
HOO69_RS05220	1151641..1153014	-	1374	WP_171801477.1	L-cystine transporter	-
HOO69_RS05225	1153204..1153920	-	717	WP_171801478.1	oxidoreductase	-
HOO69_RS05230	1154410..1155021	+	612	WP_069666192.1	flavin reductase family protein	-
HOO69_RS05235	1155031..1156062	+	1032	WP_171801479.1	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 12023.89 Da
• Isoelectric Point: 9.8439

>T156822 WP_171801475.1 NZ_CP053541:c1151253-1150948 [Vibrio europaeus]
MPQRHFKLSKLAQRHLIKVKEYTLDNYSELQWQRYKDTLLSGFQLLAENPDLGRDCSEIYPQGFYFHIGKHTAYFTKENG
FILIVAVLNQSLLPEKHLKRR

Nucleotide

• Length: 306 bp

>T156822 NZ_CP069071:c2864013-2863618 [Mycobacterium tuberculosis]
ATGATCTTCGTCGACACGTCCTTCTGGGCTGCACTTGGCAACGCCGGCGACGCTCGGCACGGCACCGCGAAGAGGTTGTG
GGCCAGCAAACCGCCCGTGGTGATGACCTCCAACCATGTCCTGGGCGAGACCTGGACGCTGCTCAACCGGCGCTGCGGTC
ACCGCGCGGCGGTTGCCGCCGCTGCAATCCGCTTGAGCACCGTCGTTCGCGTCGAGCACGTAACAGCCGACCTGGAAGAG
CAGGCATGGGAATGGCTTGTACGCCACGACGAGCGAGAGTACTCGTTCGTCGATGCCACGAGCTTCGCGGTGATGCGAAA
GAAAGGCATCCAAAATGCGTATGCCTTCGATGGTGACTTCAGCGCGGCCGGATTTGTCGAGGTAAGACCCGAGTAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9026.28 Da
• Isoelectric Point: 4.8604

>AT156822 WP_171801476.1 NZ_CP053541:c1151504-1151262 [Vibrio europaeus]
MNTLTANDAKRNFGELLLSAQREPVKISKNSKDAVIVMSIKDYEELESMKAEYLKHCFESAKKDLAEGNTIDGESFLKEL

Nucleotide

• Length: 243 bp

>AT156822 NZ_CP069071:c2864255-2864010 [Mycobacterium tuberculosis]
ATGCTAGTGGCGTATATTTGCCATGTGAAAAGGCTGCAGATCTACATCGACGAAGACGTTGACCGAGCGCTTGCTGTTGA
AGCGCGACGGCGGCGGACGTCGAAGGCGGCGCTGATCCGGGAGTACGTCGCTGAGCACCTCCGGCAGCCGGGCCCAGATC
CGGTCGATGCCTTCGTCGGATCGTTCGTGGGGGAAGCCGACTTGTCCGCGTCCGTCGACGACGTGGTTTACGGAAAGCAC
GAATGA