Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-shpB/BrnT-BrnA
Location 2617385..2617851 Replicon chromosome
Accession NZ_CP053482
Organism Thiothrix sp. Ku-5

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag HMY34_RS12945 Protein ID WP_202715889.1
Coordinates 2617385..2617576 (+) Length 64 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag HMY34_RS12950 Protein ID WP_202715890.1
Coordinates 2617573..2617851 (+) Length 93 a.a.

Genomic Context

HMY34_RS12915HMY34_RS12935HMY34_RS12940HMY34_RS12945HMY34_RS12950HMY34_RS12955HMY34_RS12965HMY34_RS12970HMY34_RS12985HMY34_RS12920HMY34_RS12925HMY34_RS12930HMY34_RS12960HMY34_RS12975HMY34_RS12980
Location: 2613123..2613380 (258 bp)
Type: Others
Protein ID: WP_202715885.1
Location: 2616497..2616727 (231 bp)
Type: Others
Protein ID: Protein_2553
Location: 2616956..2617303 (348 bp)
Type: Others
Protein ID: WP_202719199.1
Location: 2617385..2617576 (192 bp)
Type: Toxin
Protein ID: WP_202715889.1
Location: 2617573..2617851 (279 bp)
Type: Antitoxin
Protein ID: WP_202715890.1
Location: 2617862..2618008 (147 bp)
Type: Others
Protein ID: Protein_2557
Location: 2618474..2619058 (585 bp)
Type: Others
Protein ID: WP_202715892.1
Location: 2619055..2619243 (189 bp)
Type: Others
Protein ID: WP_202715893.1
Location: 2620271..2621488 (1218 bp)
Type: Others
Protein ID: WP_202719200.1
Location: 2613299..2615470 (2172 bp)
Type: Others
Protein ID: WP_202715886.1
Location: 2615467..2616246 (780 bp)
Type: Others
Protein ID: WP_202715887.1
Location: 2616297..2616482 (186 bp)
Type: Others
Protein ID: WP_202715888.1
Location: 2618013..2618213 (201 bp)
Type: Others
Protein ID: WP_202715891.1
Location: 2619250..2619666 (417 bp)
Type: Others
Protein ID: WP_202715894.1
Location: 2619663..2620157 (495 bp)
Type: Others
Protein ID: WP_202715895.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HMY34_RS129152613123..2613380+258WP_202715885.1XisI protein-
HMY34_RS129202613299..2615470-2172WP_202715886.1hypothetical protein-
HMY34_RS129252615467..2616246-780WP_202715887.1hypothetical protein-
HMY34_RS129302616297..2616482-186WP_202715888.1hypothetical protein-
HMY34_RS129352616497..2616727+231Protein_2553XisI protein-
HMY34_RS129402616956..2617303+348WP_202719199.1XisI protein-
HMY34_RS129452617385..2617576+192WP_202715889.1BrnT family toxinToxin
HMY34_RS129502617573..2617851+279WP_202715890.1BrnA antitoxin family proteinAntitoxin
HMY34_RS129552617862..2618008+147Protein_2557XisI protein-
HMY34_RS129602618013..2618213-201WP_202715891.1hypothetical protein-
HMY34_RS129652618474..2619058+585WP_202715892.1SLATT domain-containing protein-
HMY34_RS129702619055..2619243+189WP_202715893.1hypothetical protein-
HMY34_RS129752619250..2619666-417WP_202715894.1hypothetical protein-
HMY34_RS129802619663..2620157-495WP_202715895.1transposase family protein-
HMY34_RS129852620271..2621488+1218WP_202719200.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-56)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(28-84)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7543.24 Da        Isoelectric Point: 4.2813

>T156818 WP_202715889.1 NZ_CP053482:2617385-2617576 [Thiothrix sp. Ku-5]
MYRKFEWDENKNRTNQQKHGVDFDTASYVFDDPNFLSEQDRIVDGEERWQTIGLVGGFEEKIL

Download         Length: 192 bp

>T156818 NZ_CP069071:2802201-2802626 [Mycobacterium tuberculosis]
GTGGCGCTGCTCGACGTCAACGCATTGGTCGCGCTGGCGTGGGACTCACACATCCACCACGCCCGGATCCGCGAGTGGTT
TACCGCCAACGCCACGCTCGGCTGGGCGACTTGCCCGCTCACCGAAGCCGGCTTCGTGCGGGTGTCGACGAACCCAAAAG
TACTTCCCAGCGCGATCGGGATCGCAGACGCTCGACGGGTCCTCGTGGCACTACGCGCCGTGGGAGGCCACCGCTTCCTG
GCTGACGACGTATCGCTCGTCGATGACGATGTTCCGTTGATCGTCGGTTATCGCCAGGTGACCGACGCCCATCTGCTGAC
ACTCGCCCGCCGGCGCGGCGTCCGCCTGGTCACCTTCGACGCCGGTGTCTTCACCCTCGCCCAACAACGCCCCAAGACGC
CAGTGGAGCTGCTGACCATCCTCTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10313.76 Da        Isoelectric Point: 6.3447

>AT156818 WP_202715890.1 NZ_CP053482:2617573-2617851 [Thiothrix sp. Ku-5]
MNRQLSDKQIAMLKALADKPDEDIDLSDIPEAGDDAWKNAVPGEFFRPIKKQITVRIDADVLAWLKSSGNGYQTRLNQVL
REAMEKTGKRAA

Download         Length: 279 bp

>AT156818 NZ_CP069071:2801974-2802195 [Mycobacterium tuberculosis]
GTGCGAACGACACTTGACCTTGACGACGATGTGATCGCCGCGGCACGTGAACTTGCCTCCAGCCAGCGCCGCTCGCTCGG
CTCGGTGATTTCCGAACTCGCACGCCGTGGTCTCATGCCCGGACGCGTCGAGGCTGACGACGGGCTGCCGGTGATCCGCG
TTCCAGCCGGGACCCCGCCGATCACACCGGAGATGGTCCGTCGCGCGCTCGATGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References