Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT3-ataR/DUF1778(antitoxin)
Location 1710375..1711150 Replicon chromosome
Accession NZ_CP053482
Organism Thiothrix sp. Ku-5

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag HMY34_RS08395 Protein ID WP_202718797.1
Coordinates 1710659..1711150 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag HMY34_RS08390 Protein ID WP_202718796.1
Coordinates 1710375..1710653 (+) Length 93 a.a.

Genomic Context

HMY34_RS08370HMY34_RS08375HMY34_RS08390HMY34_RS08395HMY34_RS08400HMY34_RS08410HMY34_RS08425HMY34_RS08380HMY34_RS08385HMY34_RS08405HMY34_RS08415HMY34_RS08420
Location: 1705808..1707949 (2142 bp)
Type: Others
Protein ID: Protein_1644
Location: 1708009..1708686 (678 bp)
Type: Others
Protein ID: WP_202718793.1
Location: 1710375..1710653 (279 bp)
Type: Antitoxin
Protein ID: WP_202718796.1
Location: 1710659..1711150 (492 bp)
Type: Toxin
Protein ID: WP_202718797.1
Location: 1711283..1711960 (678 bp)
Type: Others
Protein ID: WP_202718798.1
Location: 1713072..1713293 (222 bp)
Type: Others
Protein ID: WP_202718800.1
Location: 1714785..1715981 (1197 bp)
Type: Others
Protein ID: WP_202718802.1
Location: 1708683..1709693 (1011 bp)
Type: Others
Protein ID: WP_202718794.1
Location: 1709705..1710061 (357 bp)
Type: Others
Protein ID: WP_202718795.1
Location: 1711957..1712967 (1011 bp)
Type: Others
Protein ID: WP_202718799.1
Location: 1713272..1713631 (360 bp)
Type: Others
Protein ID: WP_202718801.1
Location: 1713647..1714678 (1032 bp)
Type: Others
Protein ID: WP_202719163.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HMY34_RS083701705808..1707949+2142Protein_1644YgiQ family radical SAM protein-
HMY34_RS083751708009..1708686+678WP_202718793.1HNH endonuclease-
HMY34_RS083801708683..1709693-1011WP_202718794.1DNA cytosine methyltransferase-
HMY34_RS083851709705..1710061-357WP_202718795.1MarR family transcriptional regulator-
HMY34_RS083901710375..1710653+279WP_202718796.1DUF1778 domain-containing proteinAntitoxin
HMY34_RS083951710659..1711150+492WP_202718797.1GNAT family N-acetyltransferaseToxin
HMY34_RS084001711283..1711960+678WP_202718798.1HNH endonuclease-
HMY34_RS084051711957..1712967-1011WP_202718799.1DNA cytosine methyltransferase-
HMY34_RS084101713072..1713293+222WP_202718800.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
HMY34_RS084151713272..1713631-360WP_202718801.1DUF2007 domain-containing protein-
HMY34_RS084201713647..1714678-1032WP_202719163.1CDP-6-deoxy-delta-3,4-glucoseen reductase-
HMY34_RS084251714785..1715981+1197WP_202718802.1formate-dependent phosphoribosylglycinamide formyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-144)

Antitoxin

Vibrio phage ICP1, Orf50

(10-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18116.01 Da        Isoelectric Point: 9.0802

>T156817 WP_202718797.1 NZ_CP053482:1710659-1711150 [Thiothrix sp. Ku-5]
MQIIPFNPAIARDAFDCGESALNHYLQQLAGQHSRKNVSRTFVAIDNDTVTGFYSLSMAESQLEDLPAATRKKLPPQYPV
PVARLSRLAVDKTCQGQRMGELLLMNALARCARIAGEIGTVGIIVDAKHEQAQRFYLKYGFTPYTTKPLTLFIPMQTVMQ
SLP

Download         Length: 492 bp

>T156817 NZ_CP069071:c2398134-2397817 [Mycobacterium tuberculosis]
ATGACGCGCAGGCTGCGCGTCCATAACGGGGTTGAAGACGACCTATTCGAGGCGTTTTCCTACTACGCGGACGCGGCGCC
AGATCAGATCGATCGGCTTTACAACTTGTTTGTCGATGCCGTGACGAAGCGGATTCCGCAGGCTCCGAACGCGTTTGCGC
CGTTATTCAAGCACTATCGACACATCTACCTCCGGCCCTTCAGGTACTACGTTGCCTATCGGACGACCGACGAGGCTATC
GACATACTGGCTGTTCGGCACGGAATGGAGAACCCGAACGCGGTCGAGGCTGAGATCTCTGGCCGCACCTTCGAGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10264.81 Da        Isoelectric Point: 7.2042

>AT156817 WP_202718796.1 NZ_CP053482:1710375-1710653 [Thiothrix sp. Ku-5]
MPSTAAKDDRISIRTPPELKRMLIAAAAVSNISMTDFLLNAARKAAETVLAESRQITLNQQEWDRFMDLLDNPPPPNAAL
RAAMQRHHTLLD

Download         Length: 279 bp

>AT156817 NZ_CP069071:c2398346-2398131 [Mycobacterium tuberculosis]
GTGGTGGTCAACCGGGCATTGCTGGCGAGCGTCGACGCACTGTCGCGTGATGAGCAGATTGAGCTCGTCGAGCACATCAA
CGGAAACCTAGCCGAGGGCATGCATATCAGCGAGGCCAACCAGGCGCTCATCGAAGCGCGGGCCAATGACACCGACGATG
CTCATTGGTCCACCATTGATGACTTCGACAAGCGGATCCGCGCCCGGCTCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References