Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 102598..103244 Replicon chromosome
Accession NZ_CP053482
Organism Thiothrix sp. Ku-5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HMY34_RS00455 Protein ID WP_202717212.1
Coordinates 102598..102990 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HMY34_RS00460 Protein ID WP_202717213.1
Coordinates 102984..103244 (-) Length 87 a.a.

Genomic Context

HMY34_RS00430HMY34_RS00445HMY34_RS00465HMY34_RS00470HMY34_RS00475HMY34_RS00480HMY34_RS00485HMY34_RS00435HMY34_RS00440HMY34_RS00450HMY34_RS00455HMY34_RS00460
Location: 98034..99371 (1338 bp)
Type: Others
Protein ID: WP_202717207.1
Location: 101016..101573 (558 bp)
Type: Others
Protein ID: WP_202717210.1
Location: 103391..103960 (570 bp)
Type: Others
Protein ID: WP_202717214.1
Location: 103957..104877 (921 bp)
Type: Others
Protein ID: WP_202717215.1
Location: 104912..105241 (330 bp)
Type: Others
Protein ID: WP_202717216.1
Location: 105298..107151 (1854 bp)
Type: Others
Protein ID: WP_202717217.1
Location: 107163..108113 (951 bp)
Type: Others
Protein ID: WP_202717218.1
Location: 99355..100362 (1008 bp)
Type: Others
Protein ID: WP_202717208.1
Location: 100359..100964 (606 bp)
Type: Others
Protein ID: WP_202717209.1
Location: 101580..102611 (1032 bp)
Type: Others
Protein ID: WP_202717211.1
Location: 102598..102990 (393 bp)
Type: Toxin
Protein ID: WP_202717212.1
Location: 102984..103244 (261 bp)
Type: Antitoxin
Protein ID: WP_202717213.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HMY34_RS0043098034..99371+1338WP_202717207.1exodeoxyribonuclease VII large subunit-
HMY34_RS0043599355..100362-1008WP_202717208.1hypothetical protein-
HMY34_RS00440100359..100964-606WP_202717209.1DUF938 domain-containing protein-
HMY34_RS00445101016..101573+558WP_202717210.1thermonuclease family protein-
HMY34_RS00450101580..102611-1032WP_202717211.1EF-P beta-lysylation protein EpmB-
HMY34_RS00455102598..102990-393WP_202717212.1type II toxin-antitoxin system VapC family toxinToxin
HMY34_RS00460102984..103244-261WP_202717213.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
HMY34_RS00465103391..103960+570WP_202717214.1elongation factor P-
HMY34_RS00470103957..104877+921WP_202717215.1EF-P lysine aminoacylase GenX-
HMY34_RS00475104912..105241+330WP_202717216.1preprotein translocase subunit YajC-
HMY34_RS00480105298..107151+1854WP_202717217.1protein translocase subunit SecD-
HMY34_RS00485107163..108113+951WP_202717218.1protein translocase subunit SecF-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-122)

Antitoxin

Antitoxin VapB-like

(1-81)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14342.45 Da        Isoelectric Point: 4.6268

>T156812 WP_202717212.1 NZ_CP053482:c102990-102598 [Thiothrix sp. Ku-5]
VVIDTSAIIAILLGEPEAEALSKAILDDPKRLMSAFSLLECSIVIESRKGEAGGRELDLLLYRLQVEIVDMNEEQTQLAR
AGWRQFGKGRHRAALNIGDCCSYALAKYTGEPLLFKGDDFNHSDITYVAL

Download         Length: 393 bp

>T156812 NZ_CP069071:c2225130-2224570 [Mycobacterium tuberculosis]
GTGAGCGATGCCCTCGATGAAGGGCTCGTCCAGCGTATCGACGCACGCGGAACAATTGAGTGGTCGGAAACGTGCTACCG
GTATACCGGCGCGCACCGTGACGCCTTGTCCGGTGAGGGCGCGCGCAGATTCGGAGGCAGGTGGAATCCGCCGCTGCTCT
TTCCGGCGATCTATCTTGCTGATTCCGCCCAAGCCTGCATGGTTGAGGTGGAACGGGCGGCGCAAGCGGCTTCAACGACC
GCAGAGAAGATGCTCGAGGCGGCCTACCGACTACACACGATCGACGTCACGGACCTGGCCGTCCTCGATCTGACAACCCC
GCAAGCTCGGGAAGCCGTGGGGCTCGAGAACGACGACATCTATGGCGACGACTGGTCAGGGTGCCAGGCGGTCGGACATG
CGGCCTGGTTCTTGCACATGCAAGGTGTCCTCGTGCCGGCGGCGGGCGGTGTCGGCCTCGTTGTCACCGCGTATGAACAG
CGAACTCGGCCGGGCCAACTACAACTGCGACAAAGCGTCGATCTGACGCCTGCTCTTTACCAAGAACTTCGAGCCACGTA
G

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9893.33 Da        Isoelectric Point: 5.1297

>AT156812 WP_202717213.1 NZ_CP053482:c103244-102984 [Thiothrix sp. Ku-5]
MALSIRNERAEQLAREIAQLTGYNMTSAIIMALEEKLERLQRFRRVNGKLDEIMVISRRCSALPDLDTRSADDILGYDEH
GVNTLW

Download         Length: 261 bp

>AT156812 NZ_CP069071:c2225468-2225127 [Mycobacterium tuberculosis]
ATGGGAGTAAATGTGCTCGCCTCGACCGTGTCGGGTGCGATCGAGCGCTTGGGATTGACCTACGAGGAAGTCGGTGACAT
CGTCGATGCCTCGCCGCGTTCCGTGGCGCGATGGACCGCAGGTCAGGTGGTTCCCCAACGCCTCAACAAGCAACGACTTA
TCGAGCTGGCCTATGTCGCCGACGCCCTCGCGGAAGTGCTGCCGCGTGACCAGGCGAACGTGTGGATGTTTTCGCCGAAT
CGGTTACTGGAACACCGCAAGCCTGCCGACCTCGTGCGAGACGGCGAGTACCAACGCGTGTTGGCGCTCATCGACGCGAT
GGCGGAGGGAGTGTTCGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References