Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3742709..3743234 Replicon chromosome
Accession NZ_CP053398
Organism Serratia plymuthica strain C-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HL670_RS17150 Protein ID WP_062792950.1
Coordinates 3742950..3743234 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HL670_RS17145 Protein ID WP_041416850.1
Coordinates 3742709..3742960 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HL670_RS17115 3737976..3738524 + 549 WP_062792948.1 lipoprotein -
HL670_RS17120 3738781..3739509 + 729 WP_004942535.1 arginine ABC transporter ATP-binding protein ArtP -
HL670_RS17125 3739543..3740274 + 732 WP_004942530.1 arginine ABC transporter substrate-binding protein -
HL670_RS17130 3740284..3741000 + 717 WP_004942529.1 arginine ABC transporter permease ArtQ -
HL670_RS17135 3741000..3741668 + 669 WP_004942528.1 arginine ABC transporter permease ArtM -
HL670_RS17140 3741875..3742609 + 735 WP_004942526.1 arginine ABC transporter substrate-binding protein -
HL670_RS17145 3742709..3742960 + 252 WP_041416850.1 prevent-host-death protein Antitoxin
HL670_RS17150 3742950..3743234 + 285 WP_062792950.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HL670_RS17155 3743231..3744358 - 1128 WP_062792952.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
HL670_RS17160 3744429..3744908 - 480 WP_004942523.1 YbjO family protein -
HL670_RS17165 3745011..3745856 - 846 WP_004942522.1 putrescine ABC transporter permease PotI -
HL670_RS17170 3745853..3746812 - 960 WP_086016614.1 putrescine ABC transporter permease PotH -
HL670_RS17175 3746843..3747976 - 1134 WP_037432607.1 putrescine ABC transporter ATP-binding subunit PotG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10832.80 Da        Isoelectric Point: 10.0293

>T156769 WP_062792950.1 NZ_CP053398:3742950-3743234 [Serratia plymuthica]
MTYSLEFEEHALKEFKKLAPVLRDQFKKKLATVLENPCIPANRLSGLSDCYKIKLKASGYRLVYRVIDEEIVVLVLSIGK
RERSEAYTAAKKRL

Download         Length: 285 bp

>T156769 NZ_CP069070:c3144108-3143224 [Mycobacterium tuberculosis]
GTGGCCGGTCTGACCCGTGCGCTCGTTGCGCGTCACGCTCTTGGTCGGGCCGAGGCATACGACGCCGCTCTGCTCGACGT
CGCCCAGGACCACCTGCTGTACCTGCTGTCGCAGACCGTCCAGTTCGGCGATAACCGCCTGGTGTTCAAAGGCGGTACCA
GCTTACGGAAGTGCCGGCTGGGCAACGTCGGGCGGTTCTCCACTGATCTGGACTTCAGCGCGCCCGACGATGAGGTCGTG
CTGGAGGTGTGCGAGCTGATCGACGGCGCCCGTGTCGGCGGCTTCGAATTCGGCGTGCAGAGCACACGAGGCGACGGCCG
GCATTGGCAGTTGCGGGTGCGGCACACGGAATTGGGCGAGCCCCGGATCGTCGCCAGCGTCGAGTTCGCACGGCGGCCGT
TGGCTTTGCCGTCTGAGCTGCTCGCATTCATCCAGTTGCCGATCCATAAGGCTTACGGTTTTGGGCTGCCGACACTGCCG
GTCGTGGCAGAAGCGGAAGCCTGCGCAGAGAAACTCGCGCGGTACCGCCGCGTTGCGCTGGCACGGGACCTGTACGACCT
GAACCACTTCGCCTCGCGAACGATTGACGAACCGCTCGTGCGGCGGCTGTGGGTGCTCAAGGTGTGGGGTGATGTCGTCG
ATGACCGGCGCGGCACCCGGCCACTACGCGTCGAAGACGTCCTCGCCGCCCGCAGCGAGCACGACTTCCAGCCCGACTCG
ATCGGCGTGCTGACCCGTCCTGTCGCTATGGCTGCCTGGGAAGCTCGCGTTCGGAAGCGATTTGCGTTCCTCACTGACCT
CGACGCCGACGAGCAGCGGTGGGCCGCCTGCGACGAACGGCACCGCCGCGAAGTGGAGAACGCGCTGGCGGTGCTGCGGT
CCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9083.38 Da        Isoelectric Point: 6.2821

>AT156769 WP_041416850.1 NZ_CP053398:3742709-3742960 [Serratia plymuthica]
MIVQPILANSAVSISDFKKSPNTALKEANGQPVAVLTNGKISGYYVSPETWEAISEYLEDIELAKTARSRMSGKRIKVNL
DDL

Download         Length: 252 bp

>AT156769 NZ_CP069070:c3144998-3144111 [Mycobacterium tuberculosis]
GTGGTGAGCCCAGCCGGCGCCGATCGGCGCATCCCCACGTGGGCGTCACGGGTGGTGTCCGGCCTCGCTCGCGATCGGCC
CGTAGTCGTCACGAAAGAGGATCTGACGCAACGGCTTACAGAGGCTGGGTGTGGACGCGACCCCGACTCCGCCATCCGCG
AACTGCGCCGCATTGGGTGGCTGGTCCAACTGCCGGTGAAAGGCACCTGGGCATTCATTCCCCCCGGCGAGGCCGCCATC
TCGGACCCGTATCTACCGCTGCGCTCGTGGCTGGCCCGTGACCAGAACGCGGGCTTCATGCTGGCCGGTGCATCCGCAGC
GTGGCACCTCGGATACCTGGACCGCCAACCCGACGGCCGCATCCCGATCTGGCTGCCGCCGGCCAAAAGGCTGCCCGACG
GCCTAGCATCGTATGTGTCCGTCGTGCGCATCCCCTGGAACGCGGCGGACACCGCACTGCTGGCTCCGCGTCCCGCGTTG
CTGGTCCGGCGGCGGCTCGACCTCGTCGCGTGGGCGACCGGGTTACCGGCGCTAGGACCAGAAGCATTACTTGTGCAAAT
CGCCACGCGCCCGGCCTCGTTCGGGCCGTGGGCCGACCTTGTCCCCCACCTTGACGACCTCGTCGCCGACTGCAGTGACG
AGCGCCTGGAGCGTCTACTGTCGGGCCGGCCGACATCGGCCTGGCAGCGTGCAAGCTACCTGCTGGACTCGGGCGGTGAA
CCGGCACGAGGCCAGGCGCTGCTGGCCAAGCGGCACACCGAAGTGATGCCGGTGACTCGATTCACCACCGCGCACAGCCG
CGACCGTGGCGAGAGTGTCTGGGCTCCCGAGTATCAGCTTGTCGACGAGCTCGTCGTACCGCTGCTGCGCGTGATCGGCA
AGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References