Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3742709..3743234 Replicon chromosome
Accession NZ_CP053398
Organism Serratia plymuthica strain C-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HL670_RS17150 Protein ID WP_062792950.1
Coordinates 3742950..3743234 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HL670_RS17145 Protein ID WP_041416850.1
Coordinates 3742709..3742960 (+) Length 84 a.a.

Genomic Context

HL670_RS17115HL670_RS17120HL670_RS17125HL670_RS17130HL670_RS17135HL670_RS17140HL670_RS17145HL670_RS17150HL670_RS17155HL670_RS17160HL670_RS17165HL670_RS17170HL670_RS17175
Location: 3737976..3738524 (549 bp)
Type: Others
Protein ID: WP_062792948.1
Location: 3738781..3739509 (729 bp)
Type: Others
Protein ID: WP_004942535.1
Location: 3739543..3740274 (732 bp)
Type: Others
Protein ID: WP_004942530.1
Location: 3740284..3741000 (717 bp)
Type: Others
Protein ID: WP_004942529.1
Location: 3741000..3741668 (669 bp)
Type: Others
Protein ID: WP_004942528.1
Location: 3741875..3742609 (735 bp)
Type: Others
Protein ID: WP_004942526.1
Location: 3742709..3742960 (252 bp)
Type: Antitoxin
Protein ID: WP_041416850.1
Location: 3742950..3743234 (285 bp)
Type: Toxin
Protein ID: WP_062792950.1
Location: 3743231..3744358 (1128 bp)
Type: Others
Protein ID: WP_062792952.1
Location: 3744429..3744908 (480 bp)
Type: Others
Protein ID: WP_004942523.1
Location: 3745011..3745856 (846 bp)
Type: Others
Protein ID: WP_004942522.1
Location: 3745853..3746812 (960 bp)
Type: Others
Protein ID: WP_086016614.1
Location: 3746843..3747976 (1134 bp)
Type: Others
Protein ID: WP_037432607.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HL670_RS171153737976..3738524+549WP_062792948.1lipoprotein-
HL670_RS171203738781..3739509+729WP_004942535.1arginine ABC transporter ATP-binding protein ArtP-
HL670_RS171253739543..3740274+732WP_004942530.1arginine ABC transporter substrate-binding protein-
HL670_RS171303740284..3741000+717WP_004942529.1arginine ABC transporter permease ArtQ-
HL670_RS171353741000..3741668+669WP_004942528.1arginine ABC transporter permease ArtM-
HL670_RS171403741875..3742609+735WP_004942526.1arginine ABC transporter substrate-binding protein-
HL670_RS171453742709..3742960+252WP_041416850.1prevent-host-death proteinAntitoxin
HL670_RS171503742950..3743234+285WP_062792950.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HL670_RS171553743231..3744358-1128WP_062792952.123S rRNA (uracil(747)-C(5))-methyltransferase RlmC-
HL670_RS171603744429..3744908-480WP_004942523.1YbjO family protein-
HL670_RS171653745011..3745856-846WP_004942522.1putrescine ABC transporter permease PotI-
HL670_RS171703745853..3746812-960WP_086016614.1putrescine ABC transporter permease PotH-
HL670_RS171753746843..3747976-1134WP_037432607.1putrescine ABC transporter ATP-binding subunit PotG-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10832.80 Da        Isoelectric Point: 10.0293

>T156769 WP_062792950.1 NZ_CP053398:3742950-3743234 [Serratia plymuthica]
MTYSLEFEEHALKEFKKLAPVLRDQFKKKLATVLENPCIPANRLSGLSDCYKIKLKASGYRLVYRVIDEEIVVLVLSIGK
RERSEAYTAAKKRL

Download         Length: 285 bp

>T156769 NZ_CP069070:c3144108-3143224 [Mycobacterium tuberculosis]
GTGGCCGGTCTGACCCGTGCGCTCGTTGCGCGTCACGCTCTTGGTCGGGCCGAGGCATACGACGCCGCTCTGCTCGACGT
CGCCCAGGACCACCTGCTGTACCTGCTGTCGCAGACCGTCCAGTTCGGCGATAACCGCCTGGTGTTCAAAGGCGGTACCA
GCTTACGGAAGTGCCGGCTGGGCAACGTCGGGCGGTTCTCCACTGATCTGGACTTCAGCGCGCCCGACGATGAGGTCGTG
CTGGAGGTGTGCGAGCTGATCGACGGCGCCCGTGTCGGCGGCTTCGAATTCGGCGTGCAGAGCACACGAGGCGACGGCCG
GCATTGGCAGTTGCGGGTGCGGCACACGGAATTGGGCGAGCCCCGGATCGTCGCCAGCGTCGAGTTCGCACGGCGGCCGT
TGGCTTTGCCGTCTGAGCTGCTCGCATTCATCCAGTTGCCGATCCATAAGGCTTACGGTTTTGGGCTGCCGACACTGCCG
GTCGTGGCAGAAGCGGAAGCCTGCGCAGAGAAACTCGCGCGGTACCGCCGCGTTGCGCTGGCACGGGACCTGTACGACCT
GAACCACTTCGCCTCGCGAACGATTGACGAACCGCTCGTGCGGCGGCTGTGGGTGCTCAAGGTGTGGGGTGATGTCGTCG
ATGACCGGCGCGGCACCCGGCCACTACGCGTCGAAGACGTCCTCGCCGCCCGCAGCGAGCACGACTTCCAGCCCGACTCG
ATCGGCGTGCTGACCCGTCCTGTCGCTATGGCTGCCTGGGAAGCTCGCGTTCGGAAGCGATTTGCGTTCCTCACTGACCT
CGACGCCGACGAGCAGCGGTGGGCCGCCTGCGACGAACGGCACCGCCGCGAAGTGGAGAACGCGCTGGCGGTGCTGCGGT
CCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9083.38 Da        Isoelectric Point: 6.2821

>AT156769 WP_041416850.1 NZ_CP053398:3742709-3742960 [Serratia plymuthica]
MIVQPILANSAVSISDFKKSPNTALKEANGQPVAVLTNGKISGYYVSPETWEAISEYLEDIELAKTARSRMSGKRIKVNL
DDL

Download         Length: 252 bp

>AT156769 NZ_CP069070:c3144998-3144111 [Mycobacterium tuberculosis]
GTGGTGAGCCCAGCCGGCGCCGATCGGCGCATCCCCACGTGGGCGTCACGGGTGGTGTCCGGCCTCGCTCGCGATCGGCC
CGTAGTCGTCACGAAAGAGGATCTGACGCAACGGCTTACAGAGGCTGGGTGTGGACGCGACCCCGACTCCGCCATCCGCG
AACTGCGCCGCATTGGGTGGCTGGTCCAACTGCCGGTGAAAGGCACCTGGGCATTCATTCCCCCCGGCGAGGCCGCCATC
TCGGACCCGTATCTACCGCTGCGCTCGTGGCTGGCCCGTGACCAGAACGCGGGCTTCATGCTGGCCGGTGCATCCGCAGC
GTGGCACCTCGGATACCTGGACCGCCAACCCGACGGCCGCATCCCGATCTGGCTGCCGCCGGCCAAAAGGCTGCCCGACG
GCCTAGCATCGTATGTGTCCGTCGTGCGCATCCCCTGGAACGCGGCGGACACCGCACTGCTGGCTCCGCGTCCCGCGTTG
CTGGTCCGGCGGCGGCTCGACCTCGTCGCGTGGGCGACCGGGTTACCGGCGCTAGGACCAGAAGCATTACTTGTGCAAAT
CGCCACGCGCCCGGCCTCGTTCGGGCCGTGGGCCGACCTTGTCCCCCACCTTGACGACCTCGTCGCCGACTGCAGTGACG
AGCGCCTGGAGCGTCTACTGTCGGGCCGGCCGACATCGGCCTGGCAGCGTGCAAGCTACCTGCTGGACTCGGGCGGTGAA
CCGGCACGAGGCCAGGCGCTGCTGGCCAAGCGGCACACCGAAGTGATGCCGGTGACTCGATTCACCACCGCGCACAGCCG
CGACCGTGGCGAGAGTGTCTGGGCTCCCGAGTATCAGCTTGTCGACGAGCTCGTCGTACCGCTGCTGCGCGTGATCGGCA
AGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References