Detailed information of TA system TA156753

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 459072..459713
• Replicon: chromosome
• Accession: NZ_CP053391
• Organism: Acinetobacter lactucae isolate QL-1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: R8Z3I7
• Locus tag: HLV59_RS02250
• Protein ID: WP_016143557.1
• Coordinates: 459324..459713 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: HLV59_RS02245
• Protein ID: WP_171068080.1
• Coordinates: 459072..459317 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HLV59_RS02225	454574..455581	+	1008	WP_002116730.1	DNA-directed RNA polymerase subunit alpha	-
HLV59_RS02230	455600..455977	+	378	WP_002049717.1	50S ribosomal protein L17	-
HLV59_RS02235	456159..457649	+	1491	WP_171429242.1	SidA/IucD/PvdA family monooxygenase	-
HLV59_RS02240	457699..458871	-	1173	WP_016143559.1	acyl-CoA dehydrogenase family protein	-
HLV59_RS02245	459072..459317	+	246	WP_171068080.1	succinate dehydrogenase assembly factor 2	Antitoxin
HLV59_RS02250	459324..459713	+	390	WP_016143557.1	hypothetical protein	Toxin
HLV59_RS02255	460484..461572	+	1089	WP_014207738.1	hypothetical protein	-
HLV59_RS02260	461657..462232	+	576	WP_031949421.1	rhombosortase	-
HLV59_RS02265	462412..464607	+	2196	WP_016143554.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15620.65 Da
• Isoelectric Point: 8.7137

>T156753 WP_016143557.1 NZ_CP053391:459324-459713 [Acinetobacter lactucae]
MIKELNFELKYSRVSVIFQLFIGLGLAILLYQLLMPIWWLCAVIFIFIGFIFFLKQTQISQIEYLDQKLWSVAYYSEKEI
YRAEIRKIIDYQMFVVIYFEGTSAKATTVWFDQLSIEQWKRLKVLEKLY

Nucleotide

• Length: 390 bp

>T156753 NZ_CP069070:2308834-2309268 [Mycobacterium tuberculosis]
ATGAAGATCGTCGACGCGAACGTCTTGCTCTACGCCGTGAACACCACAAGTGAGCACCACAAGCCGTCGCTGCGCTGGCT
TGACGGTGCGCTGTCGGGCGCCGACCGCGTCGGGTTCGCCTGGGTGCCGTTGTTGGCGTTCGTGCGATTGGCGACCAAGG
TGGGGTTGTTCCCCCGTCCGCTTCCGCGGGAGGCGGCCATCACCCAGGTCGCGGATTGGCTAGCCGCACCCAGCGCCGTC
TTGGTGAATCCGACCGTCCGGCACGCCGATATCCTGGCGAGAATGCTGACGTACGTGGGAACCGGTGCCAACCTGGTCAA
CGACGCGCATCTGGCCGCGCTTGCCGTCGAGCATCGCGCCAGCATCGTGTCCTACGACAGTGACTTCGGCCGATTCGAAG
GGGTGCGCTGGGATCAGCCGCCCGCGCTGTTGTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9789.25 Da
• Isoelectric Point: 4.8839

>AT156753 WP_171068080.1 NZ_CP053391:459072-459317 [Acinetobacter lactucae]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKAAPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLKQYVH
G

Nucleotide

• Length: 246 bp

>AT156753 NZ_CP069070:2308573-2308827 [Mycobacterium tuberculosis]
ATGCGGACGACTGTCACATTGGATGACGACGTCGAGCAGTTGGTAAGGCGCCGGATGGCCGAGCGGCAAGTGTCCTTCAA
GAAGGCCCTCAACGACGCGATTCGCGACGGCGCCTCCGGGCGACCTGCGCCGAGTCACTTCAGCACCCGCACGGCAGACT
TGGGCGTCCCTGCGGTCAACCTCGACCGGGCCTTGCAGCTTGCGGCCGACCTCGAGGACGAAGAGCTTGTGCGCCGTCAA
CGCCGCGGGTCATAG

Structures

Toxin

• AlphaFold DB: R8Z3I7