Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1944310..1944455 Replicon chromosome
Accession NZ_CP053358
Organism Klebsiella pneumoniae strain EGKP6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1944346..1944448 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1944310..1944455 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HMI21_RS09400 1939440..1941500 + 2061 WP_004151449.1 oligopeptidase B -
HMI21_RS09405 1941504..1942163 - 660 WP_002911407.1 exodeoxyribonuclease X -
HMI21_RS09410 1942242..1942472 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HMI21_RS09415 1942585..1942959 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HMI21_RS09420 1942963..1943832 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HMI21_RS09425 1943849..1944187 + 339 WP_002911404.1 YebY family protein -
- 1944310..1944455 - 146 - - Antitoxin
- 1944346..1944448 + 103 - - Toxin
HMI21_RS09430 1944823..1944966 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HMI21_RS09435 1945071..1946039 - 969 WP_004151446.1 VirK/YbjX family protein -
HMI21_RS09440 1946196..1946849 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
HMI21_RS09445 1946846..1947037 - 192 WP_002911395.1 YebW family protein -
HMI21_RS09450 1947135..1947374 - 240 WP_002911393.1 YebV family protein -
HMI21_RS09455 1947490..1948923 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T156673 NZ_CP053358:1944346-1944448 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT156673 NZ_CP053358:c1944455-1944310 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References