Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 700146..700627 Replicon chromosome
Accession NZ_CP053344
Organism Herbiconiux sp. SALV-R1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HL652_RS03450 Protein ID WP_171704004.1
Coordinates 700364..700627 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag HL652_RS03445 Protein ID WP_171704003.1
Coordinates 700146..700367 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HL652_RS03445 700146..700367 + 222 WP_171704003.1 CopG family transcriptional regulator Antitoxin
HL652_RS03450 700364..700627 + 264 WP_171704004.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HL652_RS03455 700654..701109 - 456 WP_171704005.1 hypothetical protein -
HL652_RS03460 701187..701648 - 462 WP_171704006.1 GNAT family N-acetyltransferase -
HL652_RS03465 701861..702475 + 615 WP_171704007.1 hypothetical protein -
HL652_RS03470 702472..703008 + 537 WP_171704008.1 hypothetical protein -
HL652_RS03475 703072..703803 - 732 WP_171704009.1 SDR family oxidoreductase -
HL652_RS03480 703953..704363 + 411 WP_171707159.1 MerR family transcriptional regulator -
HL652_RS03485 704627..705160 + 534 WP_171707160.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 683889..713242 29353


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10334.98 Da        Isoelectric Point: 10.7774

>T156626 WP_171704004.1 NZ_CP053344:700364-700627 [Herbiconiux sp. SALV-R1]
MTRWKVETSPEFDKAFRKLDRAVAKRVLVYLDGLLELDDPRSRGKRLSGDLGDFWRYRIGDYRLVVRVRDQQLIVVAVQI
GHRSRIY

Download         Length: 264 bp

>T156626 NZ_CP069068:c1582213-1581812 [Mycobacterium tuberculosis]
ATGATCCTTGTCGACTCCGATGTGCTGATCGCGCATTTGCGGGGTGTCGTTGCTGCTCGCGATTGGCTTGTCAGCGCCCG
CAAGGACGGACCGCTGGCGATCAGCGTGGTGTCCACCGCCGAACTCATCGGCGGAATGCGGACCGCCGAACGGCGCGAGG
TGTGGCGCCTGCTTGCATCGTTTCGGGTACAGCCAGCAACCGAGGTAATCGCACGCCGCGCCGGCGACATGATGCGCCGA
TATCGTCGCAGCCACAACCGGATTGGACTTGGCGACTATCTGATAGCTGCTACCGCCGACGTCCAGGGCCTGCAATTGGC
AACCCTCAACGTGTGGCATTTCCCCATGTTCGAGCAGCTGAAACCACCATTTGCGGTGCCGGGGCACCGACCGCGGGCAT
GA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 7986.68 Da        Isoelectric Point: 4.1589

>AT156626 WP_171704003.1 NZ_CP053344:700146-700367 [Herbiconiux sp. SALV-R1]
VSLSIDLSDEEERRIAAVTARTGQPAAEFVHEAIVTHLDEADDTEWAENAARDWAASGSPSRPLSELRRELGL

Download         Length: 222 bp

>AT156626 NZ_CP069068:c1582467-1582210 [Mycobacterium tuberculosis]
ATGAAGCGGACCAACATCTACCTCGACGAGGAGCAGACGGCAAGCCTCGACAAGTTGGCCGCGCAAGAAGGTGTTTCGCG
CGCCGAGCTGATCCGCCTCCTGCTGAACCGAGCCCTCACCACCGCTGGGGACGACCTTGCATCGGACCTGCAGGCTATAA
ACGATTCGTTCGGCACGCTTCGCCACCTGGATCCGCCGGTGCGTCGCTCCGGTGGTCGTGAACAGCACCTTGCCCAGGTG
TGGCGCGCCACCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References