Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2227588..2227856 Replicon chromosome
Accession NZ_CP053296
Organism Escherichia coli strain M1/5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2227716..2227818 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2227588..2227856 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HLK60_RS10345 2224141..2224803 - 663 WP_000944256.1 exodeoxyribonuclease X -
HLK60_RS10350 2224827..2225483 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
HLK60_RS10355 2225585..2225815 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HLK60_RS10360 2225954..2226328 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HLK60_RS10365 2226332..2227204 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HLK60_RS10370 2227217..2227558 + 342 WP_000984819.1 YebY family protein -
- 2227588..2227856 - 269 - - Antitoxin
- 2227716..2227818 + 103 - - Toxin
HLK60_RS10375 2227953..2228609 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
HLK60_RS10380 2228610..2228801 - 192 WP_024186842.1 YebW family protein -
HLK60_RS10385 2228906..2229142 - 237 WP_001295499.1 DUF1480 family protein -
HLK60_RS10390 2229261..2230700 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T156584 NZ_CP053296:2227716-2227818 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT156584 NZ_CP053296:c2227856-2227588 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References