Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 1117515..1118136 | Replicon | chromosome |
Accession | NZ_CP053286 | ||
Organism | Serratia marcescens strain FZSF02 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | A0A8B4G7F9 |
Locus tag | HMI62_RS05255 | Protein ID | WP_004940313.1 |
Coordinates | 1117515..1117718 (-) | Length | 68 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | A0A2X2G5J9 |
Locus tag | HMI62_RS05260 | Protein ID | WP_004940312.1 |
Coordinates | 1117768..1118136 (-) | Length | 123 a.a. |
Genomic Context
Location: 1113212..1113550 (339 bp)
Type: Others
Protein ID: WP_004940327.1
Type: Others
Protein ID: WP_004940327.1
Location: 1113587..1114873 (1287 bp)
Type: Others
Protein ID: WP_004940322.1
Type: Others
Protein ID: WP_004940322.1
Location: 1116059..1116550 (492 bp)
Type: Others
Protein ID: WP_015376855.1
Type: Others
Protein ID: WP_015376855.1
Location: 1119050..1119763 (714 bp)
Type: Others
Protein ID: WP_171403083.1
Type: Others
Protein ID: WP_171403083.1
Location: 1119760..1120617 (858 bp)
Type: Others
Protein ID: WP_044031827.1
Type: Others
Protein ID: WP_044031827.1
Location: 1120643..1121521 (879 bp)
Type: Others
Protein ID: WP_171403084.1
Type: Others
Protein ID: WP_171403084.1
Location: 1114964..1115827 (864 bp)
Type: Others
Protein ID: WP_015376854.1
Type: Others
Protein ID: WP_015376854.1
Location: 1116615..1116929 (315 bp)
Type: Others
Protein ID: WP_015376856.1
Type: Others
Protein ID: WP_015376856.1
Location: 1117515..1117718 (204 bp)
Type: Toxin
Protein ID: WP_004940313.1
Type: Toxin
Protein ID: WP_004940313.1
Location: 1117768..1118136 (369 bp)
Type: Antitoxin
Protein ID: WP_004940312.1
Type: Antitoxin
Protein ID: WP_004940312.1
Location: 1118295..1118648 (354 bp)
Type: Others
Protein ID: WP_004940311.1
Type: Others
Protein ID: WP_004940311.1
Location: 1121629..1121769 (141 bp)
Type: Others
Protein ID: WP_004940304.1
Type: Others
Protein ID: WP_004940304.1
Location: 1121782..1122036 (255 bp)
Type: Others
Protein ID: WP_004940303.1
Type: Others
Protein ID: WP_004940303.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HMI62_RS05225 | 1113212..1113550 | + | 339 | WP_004940327.1 | P-II family nitrogen regulator | - |
HMI62_RS05230 | 1113587..1114873 | + | 1287 | WP_004940322.1 | ammonium transporter AmtB | - |
HMI62_RS05235 | 1114964..1115827 | - | 864 | WP_015376854.1 | acyl-CoA thioesterase II | - |
HMI62_RS05240 | 1116059..1116550 | + | 492 | WP_015376855.1 | YbaY family lipoprotein | - |
HMI62_RS05245 | 1116615..1116929 | - | 315 | WP_015376856.1 | MGMT family protein | - |
HMI62_RS05255 | 1117515..1117718 | - | 204 | WP_004940313.1 | hemolysin expression modulator Hha | Toxin |
HMI62_RS05260 | 1117768..1118136 | - | 369 | WP_004940312.1 | Hha toxicity modulator TomB | Antitoxin |
HMI62_RS05265 | 1118295..1118648 | - | 354 | WP_004940311.1 | hypothetical protein | - |
HMI62_RS05270 | 1119050..1119763 | + | 714 | WP_171403083.1 | ABC transporter ATP-binding protein | - |
HMI62_RS05275 | 1119760..1120617 | + | 858 | WP_044031827.1 | metal ABC transporter permease | - |
HMI62_RS05280 | 1120643..1121521 | + | 879 | WP_171403084.1 | metal ABC transporter substrate-binding protein | - |
HMI62_RS05285 | 1121629..1121769 | - | 141 | WP_004940304.1 | type B 50S ribosomal protein L36 | - |
HMI62_RS05290 | 1121782..1122036 | - | 255 | WP_004940303.1 | type B 50S ribosomal protein L31 | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 68 a.a. Molecular weight: 8107.37 Da Isoelectric Point: 6.9756
>T156557 WP_004940313.1 NZ_CP053286:c1117718-1117515 [Serratia marcescens]
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPTSVWKYVR
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPTSVWKYVR
Download Length: 204 bp
>T156557 NZ_CP069067:c759767-759330 [Mycobacterium tuberculosis]
ATGATAGTGCTCGACACCACCGTCCTCGTCTATGCCAAAGGCGCCGAGCATCCACTCCGCGATCCCTGCCGCGATCTCGT
CGCGGCAATCGCCGACGAACGCATCGCTGCGACCACCACCGCCGAGGTGATCCAGGAGTTCGTCCACGTACGCGCCCGCC
GGCGCGACCGCAGCGACGCCGCCGCGCTGGGCCGTGTGACTATGCCGAACTGCTCTCGCCGCTACTCACCATCAATCGAG
GCCACCTCGAAGCGCGGCCTGACGCTGTTCGAGACAACGCCAGGGCTTGAAGCCTGCGACGCGGTGCTCGCGGCGGTTGC
CGCAAGCGCCGGCGCGACCGCTCTTGTCTCGGCTGACCCGGCGTTCGCCGATCTGTCGGATGTCGTGCACGTCATTCCCG
ACGCGGCCGGGATGGTCAGCCTGCTCGGCGACCGCTGA
ATGATAGTGCTCGACACCACCGTCCTCGTCTATGCCAAAGGCGCCGAGCATCCACTCCGCGATCCCTGCCGCGATCTCGT
CGCGGCAATCGCCGACGAACGCATCGCTGCGACCACCACCGCCGAGGTGATCCAGGAGTTCGTCCACGTACGCGCCCGCC
GGCGCGACCGCAGCGACGCCGCCGCGCTGGGCCGTGTGACTATGCCGAACTGCTCTCGCCGCTACTCACCATCAATCGAG
GCCACCTCGAAGCGCGGCCTGACGCTGTTCGAGACAACGCCAGGGCTTGAAGCCTGCGACGCGGTGCTCGCGGCGGTTGC
CGCAAGCGCCGGCGCGACCGCTCTTGTCTCGGCTGACCCGGCGTTCGCCGATCTGTCGGATGTCGTGCACGTCATTCCCG
ACGCGGCCGGGATGGTCAGCCTGCTCGGCGACCGCTGA
Antitoxin
Download Length: 123 a.a. Molecular weight: 14261.95 Da Isoelectric Point: 4.4314
>AT156557 WP_004940312.1 NZ_CP053286:c1118136-1117768 [Serratia marcescens]
MDEYSPKRHDIAQLKFLCENLYDEGIATLGDSHHGWVNDPTSSVNLQLNELIEHIASFVMSYKIKYMDESDLSELVEEYL
DDTYTLFSSYGINDSDLRRWQKTKARLFRMFSGEDICTTMKT
MDEYSPKRHDIAQLKFLCENLYDEGIATLGDSHHGWVNDPTSSVNLQLNELIEHIASFVMSYKIKYMDESDLSELVEEYL
DDTYTLFSSYGINDSDLRRWQKTKARLFRMFSGEDICTTMKT
Download Length: 369 bp
>AT156557 NZ_CP069067:c759220-758975 [Mycobacterium tuberculosis]
ATGCTCAGCTTCCGCGCCGACGACCACGACGTCGACCTGGCCGACGCGTGGGCGCGTCGCCTACACATCGGCCGCTCCGA
GCTGCTGCGCGATGCGCTGCGACGTCACTTGGCCGCGCTGGCCGCGGACCAGGATGTCCAGGCCTACACCGAGCGACCGT
TGACGGACGACGAGAACGCACTGGCTGAGATCGCCGACTGGGGGCCGGCGGAGGACTGGGCCGACTGGGCCGATGCGGCG
CGGTGA
ATGCTCAGCTTCCGCGCCGACGACCACGACGTCGACCTGGCCGACGCGTGGGCGCGTCGCCTACACATCGGCCGCTCCGA
GCTGCTGCGCGATGCGCTGCGACGTCACTTGGCCGCGCTGGCCGCGGACCAGGATGTCCAGGCCTACACCGAGCGACCGT
TGACGGACGACGAGAACGCACTGGCTGAGATCGCCGACTGGGGGCCGGCGGAGGACTGGGCCGACTGGGCCGATGCGGCG
CGGTGA
Structures
Toxin
Loading, please wait
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B4G7F9 |
Antitoxin
Loading, please wait
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2X2G5J9 |