Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1949518..1949789 Replicon chromosome
Accession NZ_CP053259
Organism Escherichia coli strain GF3-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1949648..1949751 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1949518..1949789 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HLY12_RS09145 1946073..1946735 - 663 WP_171284190.1 exodeoxyribonuclease X -
HLY12_RS09150 1946759..1947415 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
HLY12_RS09155 1947517..1947747 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HLY12_RS09160 1947886..1948260 + 375 WP_000168738.1 CopC domain-containing protein YobA -
HLY12_RS09165 1948264..1949136 + 873 WP_044191540.1 copper homeostasis membrane protein CopD -
HLY12_RS09170 1949149..1949490 + 342 WP_000976472.1 YebY family protein -
- 1949518..1949789 - 272 - - Antitoxin
- 1949648..1949751 + 104 - - Toxin
HLY12_RS09175 1949886..1950542 + 657 WP_001718411.1 protein-serine/threonine phosphatase -
HLY12_RS09180 1950543..1950734 - 192 WP_001313035.1 YebW family protein -
HLY12_RS09185 1950839..1951075 - 237 WP_001295499.1 DUF1480 family protein -
HLY12_RS09190 1951193..1952632 - 1440 WP_001718410.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T156478 NZ_CP053259:1949648-1949751 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT156478 NZ_CP053259:c1949789-1949518 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References