Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4597583..4598160 Replicon chromosome
Accession NZ_CP053085
Organism Gemmatimonas sp. TET16

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HKW67_RS19680 Protein ID WP_206044507.1
Coordinates 4597861..4598160 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HKW67_RS19675 Protein ID WP_171227011.1
Coordinates 4597583..4597864 (+) Length 94 a.a.

Genomic Context

HKW67_RS19665HKW67_RS19670HKW67_RS19675HKW67_RS19680HKW67_RS19685HKW67_RS19690HKW67_RS19695HKW67_RS19700
Location: 4593089..4595644 (2556 bp)
Type: Others
Protein ID: WP_171227009.1
Location: 4596120..4597157 (1038 bp)
Type: Others
Protein ID: WP_171227010.1
Location: 4597583..4597864 (282 bp)
Type: Antitoxin
Protein ID: WP_171227011.1
Location: 4597861..4598160 (300 bp)
Type: Toxin
Protein ID: WP_206044507.1
Location: 4598472..4599560 (1089 bp)
Type: Others
Protein ID: WP_206044508.1
Location: 4599611..4599925 (315 bp)
Type: Others
Protein ID: WP_206044509.1
Location: 4600112..4601575 (1464 bp)
Type: Others
Protein ID: WP_206044510.1
Location: 4601714..4602349 (636 bp)
Type: Others
Protein ID: WP_171227014.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HKW67_RS196654593089..4595644+2556WP_171227009.1hypothetical protein-
HKW67_RS196704596120..4597157+1038WP_171227010.1hypothetical protein-
HKW67_RS196754597583..4597864+282WP_171227011.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
HKW67_RS196804597861..4598160+300WP_206044507.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HKW67_RS196854598472..4599560-1089WP_206044508.1redoxin domain-containing protein-
HKW67_RS196904599611..4599925-315WP_206044509.1cupin domain-containing protein-
HKW67_RS196954600112..4601575-1464WP_206044510.1epoxide hydrolase N-terminal domain-containing protein-
HKW67_RS197004601714..4602349-636WP_171227014.1response regulator transcription factor-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-79)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11495.18 Da        Isoelectric Point: 5.7424

>T156013 WP_206044507.1 NZ_CP053085:4597861-4598160 [Gemmatimonas sp. TET16]
MKVVWSPLAEQRALEAVEYIAQDRPRTAAVWLEGLLERVSQLDRFEEQGRVVSEIGIPAYREILHAPYRIIYRVDASRVV
ILTLRHVRRAWDPAEVDDA

Download         Length: 300 bp

>T156013 NZ_CP068823:3624770-3625312 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTATTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCTGCTAAAGCTCTTATTGACAGACAAAGTGGTGAACTGATTGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAGATTGGTGTTGTCAGATTAGTCATGTTAGGGGTAGCGCG
GAAATATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTAATTTTTTTGAACATGTAAAAATAATTCACCGGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAACTTTTATACTCGCCTCGGCTTTGTTCAGCTTTCAGCG
AGGCCCAATGTTTTCGGTGCTGTACCGATGTTTTTAGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10250.74 Da        Isoelectric Point: 10.0778

>AT156013 WP_171227011.1 NZ_CP053085:4597583-4597864 [Gemmatimonas sp. TET16]
MSKLRPSRDIQPVTEFRANAAQFIEQVQATGEPVILTQHGRSAAVLLDVESYEGMLDELALLRDVRQAEQQVAAGKTVTH
AAVAKRLRARLGR

Download         Length: 282 bp

>AT156013 NZ_CP068823:3624475-3624786 [Escherichia coli]
ATGCCTGGAAAAACAGTCGCTCTACCCGATATCGATAAAACGCTGAAAAATGCGCGGGTTGAACTCAAAACCAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCAGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References