Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3013950..3014734 Replicon chromosome
Accession NZ_CP053084
Organism Limnobacter sp. SAORIC-580

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HKT17_RS14105 Protein ID WP_171100912.1
Coordinates 3013950..3014354 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag HKT17_RS14110 Protein ID WP_171100914.1
Coordinates 3014465..3014734 (+) Length 90 a.a.

Genomic Context

HKT17_RS14100HKT17_RS14105HKT17_RS14110HKT17_RS14120HKT17_RS14125HKT17_RS14130HKT17_RS14070HKT17_RS14075HKT17_RS14080HKT17_RS14085HKT17_RS14090HKT17_RS14095HKT17_RS14115
Location: 3013686..3013946 (261 bp)
Type: Others
Protein ID: WP_171100910.1
Location: 3013950..3014354 (405 bp)
Type: Toxin
Protein ID: WP_171100912.1
Location: 3014465..3014734 (270 bp)
Type: Antitoxin
Protein ID: WP_171100914.1
Location: 3016110..3017048 (939 bp)
Type: Others
Protein ID: WP_171100919.1
Location: 3017054..3018010 (957 bp)
Type: Others
Protein ID: WP_171100920.1
Location: 3018333..3018977 (645 bp)
Type: Others
Protein ID: WP_205882445.1
Location: 3009460..3009753 (294 bp)
Type: Others
Protein ID: WP_171100899.1
Location: 3009839..3010951 (1113 bp)
Type: Others
Protein ID: WP_171100901.1
Location: 3011223..3011546 (324 bp)
Type: Others
Protein ID: WP_171100903.1
Location: 3011546..3011770 (225 bp)
Type: Others
Protein ID: WP_171100905.1
Location: 3011842..3013029 (1188 bp)
Type: Others
Protein ID: WP_205882444.1
Location: 3013022..3013504 (483 bp)
Type: Others
Protein ID: WP_171100908.1
Location: 3014859..3016025 (1167 bp)
Type: Others
Protein ID: WP_171100917.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HKT17_RS140703009460..3009753-294WP_171100899.1XRE family transcriptional regulator-
HKT17_RS140753009839..3010951-1113WP_171100901.1glycosyltransferase-
HKT17_RS140803011223..3011546-324WP_171100903.1type II toxin-antitoxin system PemK/MazF family toxin-
HKT17_RS140853011546..3011770-225WP_171100905.1antitoxin MazE family protein-
HKT17_RS140903011842..3013029-1188WP_205882444.1lipase-
HKT17_RS140953013022..3013504-483WP_171100908.1hypothetical protein-
HKT17_RS141003013686..3013946+261WP_171100910.1type II toxin-antitoxin system Phd/YefM family antitoxin-
HKT17_RS141053013950..3014354+405WP_171100912.1type II toxin-antitoxin system VapC family toxinToxin
HKT17_RS141103014465..3014734+270WP_171100914.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
HKT17_RS141153014859..3016025-1167WP_171100917.1nucleotide sugar dehydrogenase-
HKT17_RS141203016110..3017048+939WP_171100919.1SDR family oxidoreductase-
HKT17_RS141253017054..3018010+957WP_171100920.1glycosyltransferase family 2 protein-
HKT17_RS141303018333..3018977+645WP_205882445.1FkbM family methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15318.77 Da        Isoelectric Point: 6.7233

>T156009 WP_171100912.1 NZ_CP053084:3013950-3014354 [Limnobacter sp. SAORIC-580]
MYLLDTNVISELRKAKPHGAALAWIKNIPEHLLYLSAFTLAEIQSGIERTREQDEDKAKEIELWLNKLEATFKVLPMDAK
CFRVWAKLMHRETDTALEDAMIAATALANKLTVVTRNTKDFTRFDVPLLNPFSS

Download         Length: 405 bp

>T156009 NZ_CP068823:c2794519-2794416 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9824.96 Da        Isoelectric Point: 4.4131

>AT156009 WP_171100914.1 NZ_CP053084:3014465-3014734 [Limnobacter sp. SAORIC-580]
MASPVSTTRVFNNGNSQAVRIPAEFRLNTDRVQISCNEHGDLVIHPIPAERGQALLQALQALGEVDEQFIAALEAEQENS
QPMRDREAL

Download         Length: 270 bp

>AT156009 NZ_CP068823:2794378-2794649 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References