Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3013950..3014734 Replicon chromosome
Accession NZ_CP053084
Organism Limnobacter sp. SAORIC-580

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HKT17_RS14105 Protein ID WP_171100912.1
Coordinates 3013950..3014354 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag HKT17_RS14110 Protein ID WP_171100914.1
Coordinates 3014465..3014734 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKT17_RS14070 3009460..3009753 - 294 WP_171100899.1 XRE family transcriptional regulator -
HKT17_RS14075 3009839..3010951 - 1113 WP_171100901.1 glycosyltransferase -
HKT17_RS14080 3011223..3011546 - 324 WP_171100903.1 type II toxin-antitoxin system PemK/MazF family toxin -
HKT17_RS14085 3011546..3011770 - 225 WP_171100905.1 antitoxin MazE family protein -
HKT17_RS14090 3011842..3013029 - 1188 WP_205882444.1 lipase -
HKT17_RS14095 3013022..3013504 - 483 WP_171100908.1 hypothetical protein -
HKT17_RS14100 3013686..3013946 + 261 WP_171100910.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
HKT17_RS14105 3013950..3014354 + 405 WP_171100912.1 type II toxin-antitoxin system VapC family toxin Toxin
HKT17_RS14110 3014465..3014734 + 270 WP_171100914.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
HKT17_RS14115 3014859..3016025 - 1167 WP_171100917.1 nucleotide sugar dehydrogenase -
HKT17_RS14120 3016110..3017048 + 939 WP_171100919.1 SDR family oxidoreductase -
HKT17_RS14125 3017054..3018010 + 957 WP_171100920.1 glycosyltransferase family 2 protein -
HKT17_RS14130 3018333..3018977 + 645 WP_205882445.1 FkbM family methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15318.77 Da        Isoelectric Point: 6.7233

>T156009 WP_171100912.1 NZ_CP053084:3013950-3014354 [Limnobacter sp. SAORIC-580]
MYLLDTNVISELRKAKPHGAALAWIKNIPEHLLYLSAFTLAEIQSGIERTREQDEDKAKEIELWLNKLEATFKVLPMDAK
CFRVWAKLMHRETDTALEDAMIAATALANKLTVVTRNTKDFTRFDVPLLNPFSS

Download         Length: 405 bp

>T156009 NZ_CP068823:c2794519-2794416 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9824.96 Da        Isoelectric Point: 4.4131

>AT156009 WP_171100914.1 NZ_CP053084:3014465-3014734 [Limnobacter sp. SAORIC-580]
MASPVSTTRVFNNGNSQAVRIPAEFRLNTDRVQISCNEHGDLVIHPIPAERGQALLQALQALGEVDEQFIAALEAEQENS
QPMRDREAL

Download         Length: 270 bp

>AT156009 NZ_CP068823:2794378-2794649 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References