Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 3011223..3011770 Replicon chromosome
Accession NZ_CP053084
Organism Limnobacter sp. SAORIC-580

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HKT17_RS14080 Protein ID WP_171100903.1
Coordinates 3011223..3011546 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HKT17_RS14085 Protein ID WP_171100905.1
Coordinates 3011546..3011770 (-) Length 75 a.a.

Genomic Context

HKT17_RS14060HKT17_RS14100HKT17_RS14105HKT17_RS14110HKT17_RS14055HKT17_RS14065HKT17_RS14070HKT17_RS14075HKT17_RS14080HKT17_RS14085HKT17_RS14090HKT17_RS14095HKT17_RS14115
Location: 3007438..3008178 (741 bp)
Type: Others
Protein ID: WP_171101548.1
Location: 3013686..3013946 (261 bp)
Type: Others
Protein ID: WP_171100910.1
Location: 3013950..3014354 (405 bp)
Type: Others
Protein ID: WP_171100912.1
Location: 3014465..3014734 (270 bp)
Type: Others
Protein ID: WP_171100914.1
Location: 3006666..3007226 (561 bp)
Type: Others
Protein ID: WP_171100895.1
Location: 3008175..3009470 (1296 bp)
Type: Others
Protein ID: WP_171100897.1
Location: 3009460..3009753 (294 bp)
Type: Others
Protein ID: WP_171100899.1
Location: 3009839..3010951 (1113 bp)
Type: Others
Protein ID: WP_171100901.1
Location: 3011223..3011546 (324 bp)
Type: Toxin
Protein ID: WP_171100903.1
Location: 3011546..3011770 (225 bp)
Type: Antitoxin
Protein ID: WP_171100905.1
Location: 3011842..3013029 (1188 bp)
Type: Others
Protein ID: WP_205882444.1
Location: 3013022..3013504 (483 bp)
Type: Others
Protein ID: WP_171100908.1
Location: 3014859..3016025 (1167 bp)
Type: Others
Protein ID: WP_171100917.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HKT17_RS140553006666..3007226-561WP_171100895.1hypothetical protein-
HKT17_RS140603007438..3008178+741WP_171101548.1glycosyltransferase-
HKT17_RS140653008175..3009470-1296WP_171100897.1type II toxin-antitoxin system HipA family toxin-
HKT17_RS140703009460..3009753-294WP_171100899.1XRE family transcriptional regulator-
HKT17_RS140753009839..3010951-1113WP_171100901.1glycosyltransferase-
HKT17_RS140803011223..3011546-324WP_171100903.1type II toxin-antitoxin system PemK/MazF family toxinToxin
HKT17_RS140853011546..3011770-225WP_171100905.1antitoxin MazE family proteinAntitoxin
HKT17_RS140903011842..3013029-1188WP_205882444.1lipase-
HKT17_RS140953013022..3013504-483WP_171100908.1hypothetical protein-
HKT17_RS141003013686..3013946+261WP_171100910.1type II toxin-antitoxin system Phd/YefM family antitoxin-
HKT17_RS141053013950..3014354+405WP_171100912.1type II toxin-antitoxin system VapC family toxin-
HKT17_RS141103014465..3014734+270WP_171100914.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
HKT17_RS141153014859..3016025-1167WP_171100917.1nucleotide sugar dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-102)

Antitoxin

Antitoxin MazE-like

(7-72)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11463.44 Da        Isoelectric Point: 10.0923

>T156008 WP_171100903.1 NZ_CP053084:c3011546-3011223 [Limnobacter sp. SAORIC-580]
MRGDFVTIATQGDFGKPRPALVIQSNLFQEHATLTVLPVTGTLVSAPLLRVTVHPTSENGLQKVSQIMIDKAITVKQEKV
GPAFGRLDATGLIEIERALAVFLGIAK

Download         Length: 324 bp

>T156008 NZ_CP068823:c2439188-2438910 [Escherichia coli]
ATGATAATGAATTTCAGACACAAGGGATTGCGTGACTTGTTTCTTCTCGGCAAAACCTCCGGCGTTATACCGACGCAAGT
CAAACGATTACGCCACCGACTCGCTGTGATTGATGCAGCAAGCTGTCTTGCAGATATCGATATGCCCGGTTACCGATTAC
ACCCGTTAAGCGGCGATCGCGATGGAATTTGGGCGATATCTGTCTCGGGCAACTGGCGGATAACGTTCGAGTTCGTCAAT
GGCGATGCATACATACTGGATTACGAGGACTATCACTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8232.05 Da        Isoelectric Point: 6.4508

>AT156008 WP_171100905.1 NZ_CP053084:c3011770-3011546 [Limnobacter sp. SAORIC-580]
MANSNVNSRVQKHRNSLRSAGLRPIQIWVPDTRKPGFADECARQSSVVAQSDATDQAIEHLLNESARDIDGWTD

Download         Length: 225 bp

>AT156008 NZ_CP068823:c2438910-2438626 [Escherichia coli]
ATGAAAATGGCCAATCATCCCCGCCCGGGGGACATTATTCAGGAATCACTGGACGAACTTAATGTCAGCCTGCGCGAGTT
TGCCAGAGCTATGGAAATTGCGCCCTCAACGGCAAGCCGATTGCTGACCGGAAAAGCAGCTTTGACGCCAGAAATGGCAA
TTAAACTTTCCGTGGTGATCGGCAGTTCGCCGCAAATGTGGCTGAATCTGCAAAACGCCTGGAGCCTGGCAGAGGCTGAA
AAAACGGTGGATGTGTCGCGACTGCGCCGTCTGGTTACGCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References