Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2468354..2468622 Replicon chromosome
Accession NZ_CP053080
Organism Escherichia coli strain HB37

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2468482..2468584 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2468354..2468622 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKW69_RS11640 2464906..2465568 - 663 WP_000944256.1 exodeoxyribonuclease X -
HKW69_RS11645 2465592..2466248 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
HKW69_RS11650 2466351..2466581 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HKW69_RS11655 2466720..2467094 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HKW69_RS11660 2467098..2467970 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HKW69_RS11665 2467983..2468324 + 342 WP_000984819.1 YebY family protein -
- 2468354..2468622 - 269 - - Antitoxin
- 2468482..2468584 + 103 - - Toxin
HKW69_RS11670 2468719..2469375 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
HKW69_RS11675 2469376..2469567 - 192 WP_001296140.1 YebW family protein -
HKW69_RS11680 2469672..2469908 - 237 WP_001295499.1 DUF1480 family protein -
HKW69_RS11685 2470026..2471465 - 1440 WP_001298454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T155971 NZ_CP053080:2468482-2468584 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT155971 NZ_CP053080:c2468622-2468354 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References