Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 191959..192658 Replicon chromosome
Accession NZ_CP053044
Organism Proteus terrae subsp. cibarius strain HNCF43W

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG541_RS00855 Protein ID WP_075671320.1
Coordinates 192272..192658 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG541_RS00850 Protein ID WP_075671318.1
Coordinates 191959..192279 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG541_RS00825 188178..188453 - 276 WP_004246820.1 DNA-directed RNA polymerase subunit omega -
HG541_RS00830 188508..189131 - 624 WP_006534608.1 guanylate kinase -
HG541_RS00835 189437..190054 - 618 WP_006534609.1 trimeric intracellular cation channel family protein -
HG541_RS00840 190191..191477 + 1287 WP_159242125.1 DUF3748 domain-containing protein -
HG541_RS00845 191571..191891 + 321 WP_075671316.1 hypothetical protein -
HG541_RS00850 191959..192279 - 321 WP_075671318.1 helix-turn-helix domain-containing protein Antitoxin
HG541_RS00855 192272..192658 - 387 WP_075671320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HG541_RS00860 192810..194882 - 2073 WP_075671322.1 glycine--tRNA ligase subunit beta -
HG541_RS00865 194892..195797 - 906 WP_004246832.1 glycine--tRNA ligase subunit alpha -
HG541_RS00870 196036..196620 + 585 WP_159242124.1 DNA-3-methyladenine glycosylase I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14358.75 Da        Isoelectric Point: 10.0463

>T155858 WP_075671320.1 NZ_CP053044:c192658-192272 [Proteus terrae subsp. cibarius]
MVIYKTKMFKNSFKKMPINDAALIDIANEVYAGHFEADLGGGIIKKRICIHGKGKSSGIRTIIFYKQGSNLFFADGWKKS
HLSAKKSKEITDDELESYKDLAKDLFSATKNKIDKMVALGLLTEVKHD

Download         Length: 387 bp

>T155858 NZ_CP068818:260991-261098 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12068.99 Da        Isoelectric Point: 10.0482

>AT155858 WP_075671318.1 NZ_CP053044:c192279-191959 [Proteus terrae subsp. cibarius]
MTDKMQEMLKFAQEMEVAGITDGESARRIAARIKAKELKERYAHLTPMNGEDIKRIREQNNISQSSLALILNMTKESVSK
WERNEIKPNGAALRLLNLIDNKAISI

Download         Length: 321 bp

>AT155858 NZ_CP068818:c260933-260879 [Escherichia coli]
CAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References