Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 3477711..3478456 Replicon chromosome
Accession NZ_CP053042
Organism Proteus terrae subsp. cibarius strain HNCF44W

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag HG539_RS15860 Protein ID WP_159241970.1
Coordinates 3477711..3478202 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag HG539_RS15865 Protein ID WP_075673024.1
Coordinates 3478190..3478456 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG539_RS15840 3472796..3473902 + 1107 WP_159241966.1 flagellar basal body P-ring protein FlgI -
HG539_RS15845 3473902..3474888 + 987 WP_159241967.1 flagellar assembly peptidoglycan hydrolase FlgJ -
HG539_RS15850 3475006..3476649 + 1644 WP_159241968.1 flagellar hook-associated protein FlgK -
HG539_RS15855 3476681..3477625 + 945 WP_159241969.1 flagellar hook-associated protein FlgL -
HG539_RS15860 3477711..3478202 - 492 WP_159241970.1 GNAT family N-acetyltransferase Toxin
HG539_RS15865 3478190..3478456 - 267 WP_075673024.1 DUF1778 domain-containing protein Antitoxin
HG539_RS15870 3478580..3479362 - 783 WP_099660619.1 flagellar type III secretion system protein FliR -
HG539_RS15875 3479368..3479637 - 270 WP_069367481.1 flagellar biosynthesis protein FliQ -
HG539_RS15880 3479653..3480366 - 714 WP_171455369.1 flagellar type III secretion system pore protein FliP -
HG539_RS15885 3480423..3480869 - 447 WP_075673022.1 flagellar biosynthetic protein FliO -
HG539_RS15890 3480873..3481283 - 411 WP_006533153.1 flagellar motor switch protein FliN -
HG539_RS15895 3481276..3482307 - 1032 WP_023581831.1 flagellar motor switch protein FliM -
HG539_RS15900 3482313..3482795 - 483 WP_006533151.1 flagellar basal body-associated protein FliL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(22-148)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18240.21 Da        Isoelectric Point: 10.3194

>T155855 WP_159241970.1 NZ_CP053042:c3478202-3477711 [Proteus terrae subsp. cibarius]
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAMSHIRRNM
PDPIPVIILARLAVDKTFHGKGLGADLLRDAVLRCHHVAENIGVRAIMVHALTENAKHFYLHHGFKASSIQDKILFLALK
KKI

Download         Length: 492 bp

>T155855 NZ_CP068817:c5006472-5006161 [Escherichia coli]
ATCCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTGTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10111.62 Da        Isoelectric Point: 4.5256

>AT155855 WP_075673024.1 NZ_CP053042:c3478456-3478190 [Proteus terrae subsp. cibarius]
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK

Download         Length: 267 bp

>AT155855 NZ_CP068817:c5006160-5005870 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References