Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1870837..1870982 Replicon chromosome
Accession NZ_CP053035
Organism Klebsiella pneumoniae strain P35

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1870873..1870975 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1870837..1870982 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKJ75_RS09010 1865967..1868027 + 2061 WP_004151449.1 oligopeptidase B -
HKJ75_RS09015 1868031..1868690 - 660 WP_020324964.1 exodeoxyribonuclease X -
HKJ75_RS09020 1868769..1868999 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HKJ75_RS09025 1869112..1869486 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HKJ75_RS09030 1869490..1870359 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HKJ75_RS09035 1870376..1870714 + 339 WP_002911404.1 YebY family protein -
- 1870837..1870982 - 146 - - Antitoxin
- 1870873..1870975 + 103 - - Toxin
HKJ75_RS09040 1871351..1871494 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HKJ75_RS09045 1871599..1872567 - 969 WP_004151446.1 VirK/YbjX family protein -
HKJ75_RS09050 1872724..1873377 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HKJ75_RS09055 1873374..1873565 - 192 WP_002911395.1 YebW family protein -
HKJ75_RS09060 1873663..1873902 - 240 WP_002911393.1 YebV family protein -
HKJ75_RS09065 1874018..1875451 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T155833 NZ_CP053035:1870873-1870975 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT155833 NZ_CP053035:c1870982-1870837 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References