Detailed information of TA system TA155828

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 3197834..3198350
• Replicon: chromosome
• Accession: NZ_CP053032
• Organism: Halomonas sp. PGE1

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HIR79_RS15060
• Protein ID: WP_110070795.1
• Coordinates: 3197834..3198097 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: HIR79_RS15065
• Protein ID: WP_110070796.1
• Coordinates: 3198090..3198350 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HIR79_RS15055	3196076..3197653	-	1578	WP_169958950.1	ATP-binding protein	-
HIR79_RS15060	3197834..3198097	-	264	WP_110070795.1	Txe/YoeB family addiction module toxin	Toxin
HIR79_RS15065	3198090..3198350	-	261	WP_110070796.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HIR79_RS15070	3198616..3200193	-	1578	WP_169958951.1	ATP-binding protein	-
HIR79_RS15075	3200390..3200827	+	438	WP_169958952.1	nucleotidyltransferase domain-containing protein	-
HIR79_RS15080	3200847..3201254	+	408	WP_169958953.1	DUF86 domain-containing protein	-
HIR79_RS15085	3201283..3201474	-	192	WP_169958954.1	hypothetical protein	-
HIR79_RS15090	3201479..3201823	-	345	WP_169958955.1	hypothetical protein	-
HIR79_RS15095	3201940..3203160	-	1221	WP_169958956.1	FliC/FljB family flagellin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (8-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10543.05 Da
• Isoelectric Point: 9.4471

>T155828 WP_110070795.1 NZ_CP053032:c3198097-3197834 [Halomonas sp. PGE1]
MSNRLLCWTDESWRDYVYWQRQDKKTLKRINKLIADVKRSPFEGIGKPEPLKENLSGFWSRRIDESNRLVYVVEESSITI
ISCRYHY

Nucleotide

• Length: 264 bp

>T155828 NZ_CP068816:4341989-4342330 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACTGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTCGCCTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9725.90 Da
• Isoelectric Point: 4.8053

>AT155828 WP_110070796.1 NZ_CP053032:c3198350-3198090 [Halomonas sp. PGE1]
MRVVSFTEARNGLKSVLDSVINDADTAIITRRDSEDAVVMSLDYYNSLMETVHLLRSPANAAHLNRSIEQYRSGKVVERK
LLDDDE

Nucleotide

• Length: 261 bp

>AT155828 NZ_CP068816:c4341994-4341918 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT