Detailed information of TA system TA155825

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hipBA/HipA-HipB
• Location: 2502333..2503714
• Replicon: chromosome
• Accession: NZ_CP053032
• Organism: Halomonas sp. PGE1

Toxin (Protein)

• Gene name: hipA
• Uniprot ID: -
• Locus tag: HIR79_RS11805
• Protein ID: WP_169958513.1
• Coordinates: 2502333..2503451 (-)
• Length: 373 a.a.

Antitoxin (Protein)

• Gene name: hipB
• Uniprot ID: -
• Locus tag: HIR79_RS11810
• Protein ID: WP_119023423.1
• Coordinates: 2503454..2503714 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	bplB	2477930..2577843	99913

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HipA-like, C-terminal (148-364)

Antitoxin

• Cro/C1-type helix-turn-helix domain (13-64)

Sequences

Toxin

Protein

• Length: 373 a.a.
• Molecular weight: 41591.87 Da
• Isoelectric Point: 7.3985

>T155825 WP_169958513.1 NZ_CP053032:c2503451-2502333 [Halomonas sp. PGE1]
MPNLVVAMNGIEVGVLTLARSGAMTFRYLPEWFNRAGARAISLSMPLTLSEYRGEVVYNFFDNLLPDSEDIRARMQVRFQ
LATRHPFDLLASIGRDCIGAIQLYPESSMLESVRQVTAEPVSDQDIEGLLIGYREAPLGMSQQSEFRISLAGAQEKTALL
WYEGRWQRPSGSTPTSHILKLPIGFLEHGNIDLRQSGENEWLCLQILAAFGLPVAKAALATFGTQTVLVVERFDRRWSGR
GDWLMRLPQEDFCQALGVAPALKYESDGGPGIADAMRLLLGSQEAGNDRKRFFYTQMLFWLLAAIDGHAKNFSLFLEPGS
AYRMTPLYDVISAYPLMAHGSLPRERAKMAMALKGKSRHYRWARIEPPPVSG

Nucleotide

• Length: 1119 bp

>T155825 NZ_CP068816:c3948703-3948305 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGAAGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGTGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGCAGCGCATTTGGTATATTGTCAGGGCGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9761.10 Da
• Isoelectric Point: 8.7757

>AT155825 WP_119023423.1 NZ_CP053032:c2503714-2503454 [Halomonas sp. PGE1]
VKITSPDMLAHSLKSARRQLQLTQQQAAKQVGIKQATISAFENHPEKSRIETLFKLLAVLELELHLTPRNQAEGAADKSQ
NWDQEW

Nucleotide

• Length: 261 bp

>AT155825 NZ_CP068816:c3948999-3948706 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
TGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTTGAAGCATTAATGGACATGCTTG
CAGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCGAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA