Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 2023113..2023623 Replicon chromosome
Accession NZ_CP053030
Organism Pseudomonas congelans strain 508

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DB356_RS09100 Protein ID WP_096125650.1
Coordinates 2023113..2023394 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DB356_RS09105 Protein ID WP_032611982.1
Coordinates 2023384..2023623 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DB356_RS09085 (DB356_09440) 2019252..2021180 + 1929 WP_096102892.1 methyl-accepting chemotaxis protein -
DB356_RS09090 (DB356_09445) 2021214..2022146 - 933 WP_214424213.1 DMT family transporter -
DB356_RS09095 (DB356_09450) 2022221..2023075 + 855 WP_214423931.1 LysR family transcriptional regulator -
DB356_RS09100 (DB356_09455) 2023113..2023394 - 282 WP_096125650.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DB356_RS09105 (DB356_09460) 2023384..2023623 - 240 WP_032611982.1 ribbon-helix-helix protein, CopG family Antitoxin
DB356_RS09110 (DB356_09465) 2023783..2024799 - 1017 WP_096102889.1 1-aminocyclopropane-1-carboxylate deaminase -
DB356_RS09115 (DB356_09470) 2024986..2025492 + 507 WP_010437192.1 winged helix-turn-helix transcriptional regulator -
DB356_RS09120 (DB356_09475) 2025638..2026546 + 909 WP_214423932.1 DUF808 domain-containing protein -
DB356_RS09125 (DB356_09480) 2026724..2027509 - 786 WP_003423373.1 outer membrane protein OmpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10446.13 Da        Isoelectric Point: 10.4249

>T155820 WP_096125650.1 NZ_CP053030:c2023394-2023113 [Pseudomonas congelans]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPV

Download         Length: 282 bp

>T155820 NZ_CP068816:c3162783-3162400 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGCGGCATCGCGCTGCCCGTCTCCGGTTGAAATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTTACGTTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGTGCTGGTACGAACTGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGTCTCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCG
GGACAATTACAGAATGGTAAATAACATTACCCTGGGCAAGCATCCGGAGGAGGCGAAACAATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8727.81 Da        Isoelectric Point: 4.4217

>AT155820 WP_032611982.1 NZ_CP053030:c2023623-2023384 [Pseudomonas congelans]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADADEFASPDDVKAVMNKWSGNAG

Download         Length: 240 bp

>AT155820 NZ_CP068816:c3163244-3162864 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACGCTTCCCGACGACAACAAAGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCAATGCGGATGCATACCATCTGGACCAGGCTTTTCCACTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGGCATCAGCATACCGTCACGCTGTATGCGAAAGGGCTGACCTGCGATGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCTGCGACCGAAACGGAAAGTAACCCACCGGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References