Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 1890555..1891068 Replicon chromosome
Accession NZ_CP053029
Organism Pseudomonas congelans strain TLP2

Toxin (Protein)


Gene name relE Uniprot ID A0A0N8R210
Locus tag DBV21_RS08420 Protein ID WP_010437186.1
Coordinates 1890555..1890839 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DBV21_RS08425 Protein ID WP_025991107.1
Coordinates 1890829..1891068 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBV21_RS08405 (DBV21_08735) 1886697..1888625 + 1929 WP_096102892.1 methyl-accepting chemotaxis protein -
DBV21_RS08410 (DBV21_08740) 1888659..1889591 - 933 WP_214351551.1 DMT family transporter -
DBV21_RS08415 (DBV21_08745) 1889666..1890520 + 855 WP_214350152.1 LysR family transcriptional regulator -
DBV21_RS08420 (DBV21_08750) 1890555..1890839 - 285 WP_010437186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DBV21_RS08425 (DBV21_08755) 1890829..1891068 - 240 WP_025991107.1 CopG family ribbon-helix-helix protein Antitoxin
DBV21_RS08430 (DBV21_08760) 1891228..1892244 - 1017 WP_002552793.1 1-aminocyclopropane-1-carboxylate deaminase -
DBV21_RS08435 (DBV21_08765) 1892431..1892937 + 507 WP_010437192.1 winged helix-turn-helix transcriptional regulator -
DBV21_RS08440 (DBV21_08770) 1893084..1893992 + 909 WP_122693692.1 DUF808 domain-containing protein -
DBV21_RS08445 (DBV21_08775) 1894170..1894955 - 786 WP_003423373.1 outer membrane protein OmpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10604.29 Da        Isoelectric Point: 10.4249

>T155819 WP_010437186.1 NZ_CP053029:c1890839-1890555 [Pseudomonas congelans]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPAW

Download         Length: 285 bp

>T155819 NZ_CP068816:2807625-2807732 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8669.78 Da        Isoelectric Point: 4.5535

>AT155819 WP_025991107.1 NZ_CP053029:c1891068-1890829 [Pseudomonas congelans]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASPDDVKAVMNKWSGNAG

Download         Length: 240 bp

>AT155819 NZ_CP068816:c2807572-2807511 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N8R210

Antitoxin

Source ID Structure

References