155810

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 360871..361430 Replicon plasmid p-A-Sy
Accession NZ_CP053022
Organism Sphingobium yanoikuyae strain YC-XJ2

Toxin (Protein)


Gene name relE Uniprot ID A0A084E1X2
Locus tag HH800_RS27000 Protein ID WP_017503639.1
Coordinates 361137..361430 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A084E1X1
Locus tag HH800_RS26995 Protein ID WP_017503640.1
Coordinates 360871..361140 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HH800_RS26970 356261..357121 - 861 WP_017503735.1 type IV toxin-antitoxin system AbiEi family antitoxin -
HH800_RS26975 357230..357563 - 334 Protein_341 hypothetical protein -
HH800_RS26980 357721..358107 + 387 WP_125990295.1 hypothetical protein -
HH800_RS26985 358728..360145 - 1418 Protein_343 ISNCY family transposase -
HH800_RS26990 360407..360772 + 366 WP_017503641.1 site-specific integrase -
HH800_RS26995 360871..361140 + 270 WP_017503640.1 ribbon-helix-helix domain-containing protein Antitoxin
HH800_RS27000 361137..361430 + 294 WP_017503639.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HH800_RS27005 361594..361776 + 183 Protein_347 transposase -
HH800_RS27010 361771..361887 - 117 Protein_348 transposase -
HH800_RS27015 362208..364094 - 1887 WP_017503637.1 molecular chaperone HtpG -
HH800_RS27020 365199..365801 - 603 WP_169863496.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..371560 371560


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11316.01 Da        Isoelectric Point: 9.5461

>T155810 WP_017503639.1 NZ_CP053022:361137-361430 [Sphingobium yanoikuyae]
MKIHWTTKASSDLVRLHEHLKPVAPDAAARIVQQLAHAPNRLLDYPRLGEKLEAYEPREVRRIIVGNYEMRYEIAGGTIF
VLRLWHCREHRSFGSDN

Download         Length: 294 bp

>T155810 NZ_CP068816:c830849-830475 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9819.12 Da        Isoelectric Point: 4.8380

>AT155810 WP_017503640.1 NZ_CP053022:360871-361140 [Sphingobium yanoikuyae]
MASETKVLTAHVPLGLAEKVEAVATRLERSRGWVMKQALAAWVDQEEERHKMTLEALEDVDAGRVIDHQSIQAWADSLGT
DTPLPSPTK

Download         Length: 270 bp

>AT155810 NZ_CP068816:c831307-830939 [Escherichia coli]
GTGTCAGACGCACTCTCCGGGACAATGCTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACAGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGTCTGACCTGCAAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A084E1X2

Antitoxin

Source ID Structure
AlphaFold DB A0A084E1X1

References