Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 519819..520359 Replicon chromosome
Accession NZ_CP053021
Organism Sphingobium yanoikuyae strain YC-XJ2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HH800_RS02845 Protein ID WP_169860130.1
Coordinates 520069..520359 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HH800_RS02840 Protein ID WP_169860129.1
Coordinates 519819..520055 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HH800_RS02820 514924..515772 + 849 WP_037517339.1 ferredoxin--NADP reductase -
HH800_RS02825 515943..517778 - 1836 WP_169860126.1 DUF885 family protein -
HH800_RS02830 517918..518412 - 495 WP_169860127.1 hypothetical protein -
HH800_RS02835 518505..519719 + 1215 WP_169860128.1 tetratricopeptide repeat protein -
HH800_RS02840 519819..520055 + 237 WP_169860129.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HH800_RS02845 520069..520359 + 291 WP_169860130.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HH800_RS02850 520472..520918 - 447 WP_169860131.1 NfeD family protein -
HH800_RS02855 521346..522317 - 972 WP_169860132.1 SPFH/Band 7/PHB domain protein -
HH800_RS02860 522395..523210 + 816 WP_169863200.1 CoA ester lyase -
HH800_RS02865 523227..524162 + 936 WP_169860133.1 L-lactate dehydrogenase -
HH800_RS02870 524176..525129 - 954 WP_169860134.1 quinoprotein relay system zinc metallohydrolase 1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10570.96 Da        Isoelectric Point: 7.2733

>T155805 WP_169860130.1 NZ_CP053021:520069-520359 [Sphingobium yanoikuyae]
VKRLLFTPAAQADLSDIWDYSAATWGADQADLYIDAIRDVCLALADGRRPGLPVDVRAGYRKAPAGSHMIYYRDGGDHLA
IVRVLHGRQDTGRYLA

Download         Length: 291 bp

>T155805 NZ_CP068815:c4407724-4407347 [Escherichia coli]
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8344.28 Da        Isoelectric Point: 5.7834

>AT155805 WP_169860129.1 NZ_CP053021:519819-520055 [Sphingobium yanoikuyae]
MARNTSVTIGDHFTRFISDQVQTGRYGSASDVVRAGLRLLEEREAQVQALQAALIAGEESGAATPFDFEAFKAAKRGG

Download         Length: 237 bp

>AT155805 NZ_CP068815:c4408182-4407814 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References