Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/ParE-RHH |
Location | 519819..520359 | Replicon | chromosome |
Accession | NZ_CP053021 | ||
Organism | Sphingobium yanoikuyae strain YC-XJ2 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | HH800_RS02845 | Protein ID | WP_169860130.1 |
Coordinates | 520069..520359 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | HH800_RS02840 | Protein ID | WP_169860129.1 |
Coordinates | 519819..520055 (+) | Length | 79 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HH800_RS02820 | 514924..515772 | + | 849 | WP_037517339.1 | ferredoxin--NADP reductase | - |
HH800_RS02825 | 515943..517778 | - | 1836 | WP_169860126.1 | DUF885 family protein | - |
HH800_RS02830 | 517918..518412 | - | 495 | WP_169860127.1 | hypothetical protein | - |
HH800_RS02835 | 518505..519719 | + | 1215 | WP_169860128.1 | tetratricopeptide repeat protein | - |
HH800_RS02840 | 519819..520055 | + | 237 | WP_169860129.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
HH800_RS02845 | 520069..520359 | + | 291 | WP_169860130.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HH800_RS02850 | 520472..520918 | - | 447 | WP_169860131.1 | NfeD family protein | - |
HH800_RS02855 | 521346..522317 | - | 972 | WP_169860132.1 | SPFH/Band 7/PHB domain protein | - |
HH800_RS02860 | 522395..523210 | + | 816 | WP_169863200.1 | CoA ester lyase | - |
HH800_RS02865 | 523227..524162 | + | 936 | WP_169860133.1 | L-lactate dehydrogenase | - |
HH800_RS02870 | 524176..525129 | - | 954 | WP_169860134.1 | quinoprotein relay system zinc metallohydrolase 1 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10570.96 Da Isoelectric Point: 7.2733
>T155805 WP_169860130.1 NZ_CP053021:520069-520359 [Sphingobium yanoikuyae]
VKRLLFTPAAQADLSDIWDYSAATWGADQADLYIDAIRDVCLALADGRRPGLPVDVRAGYRKAPAGSHMIYYRDGGDHLA
IVRVLHGRQDTGRYLA
VKRLLFTPAAQADLSDIWDYSAATWGADQADLYIDAIRDVCLALADGRRPGLPVDVRAGYRKAPAGSHMIYYRDGGDHLA
IVRVLHGRQDTGRYLA
Download Length: 291 bp
>T155805 NZ_CP068815:c4407724-4407347 [Escherichia coli]
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8344.28 Da Isoelectric Point: 5.7834
>AT155805 WP_169860129.1 NZ_CP053021:519819-520055 [Sphingobium yanoikuyae]
MARNTSVTIGDHFTRFISDQVQTGRYGSASDVVRAGLRLLEEREAQVQALQAALIAGEESGAATPFDFEAFKAAKRGG
MARNTSVTIGDHFTRFISDQVQTGRYGSASDVVRAGLRLLEEREAQVQALQAALIAGEESGAATPFDFEAFKAAKRGG
Download Length: 237 bp
>AT155805 NZ_CP068815:c4408182-4407814 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|