Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018501..2018646 Replicon chromosome
Accession NZ_CP053016
Organism Klebsiella pneumoniae strain KPN361

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018537..2018639 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018501..2018646 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HJ591_RS09880 2013631..2015691 + 2061 WP_004151449.1 oligopeptidase B -
HJ591_RS09885 2015695..2016354 - 660 WP_002911407.1 exodeoxyribonuclease X -
HJ591_RS09890 2016433..2016663 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HJ591_RS09895 2016776..2017150 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HJ591_RS09900 2017154..2018023 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HJ591_RS09905 2018040..2018378 + 339 WP_002911404.1 YebY family protein -
- 2018501..2018646 - 146 - - Antitoxin
- 2018537..2018639 + 103 - - Toxin
HJ591_RS09910 2019014..2019157 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HJ591_RS09915 2019262..2020230 - 969 WP_004151446.1 VirK/YbjX family protein -
HJ591_RS09920 2020387..2021040 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HJ591_RS09925 2021037..2021228 - 192 WP_002911395.1 YebW family protein -
HJ591_RS09930 2021326..2021565 - 240 WP_002911393.1 YebV family protein -
HJ591_RS09935 2021681..2023114 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T155783 NZ_CP053016:2018537-2018639 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT155783 NZ_CP053016:c2018646-2018501 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References