Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yeeU/CbtA-CbeA
Location 3572083..3572830 Replicon chromosome
Accession NZ_CP053013
Organism Dickeya zeae strain MS_2014

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag HJ580_RS15995 Protein ID WP_102802208.1
Coordinates 3572083..3572403 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag HJ580_RS16000 Protein ID WP_102802209.1
Coordinates 3572429..3572830 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HJ580_RS15975 (HJ580_15990) 3567923..3569242 + 1320 WP_102802204.1 site-specific integrase -
HJ580_RS15980 (HJ580_15995) 3569317..3570366 - 1050 WP_102802205.1 macro domain-containing protein -
HJ580_RS15985 (HJ580_16000) 3570380..3571027 - 648 WP_102802206.1 DUF4433 domain-containing protein -
HJ580_RS15990 (HJ580_16005) 3571132..3571965 - 834 WP_102802207.1 DUF4942 domain-containing protein -
HJ580_RS15995 (HJ580_16010) 3572083..3572403 - 321 WP_102802208.1 TA system toxin CbtA family protein Toxin
HJ580_RS16000 (HJ580_16015) 3572429..3572830 - 402 WP_102802209.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HJ580_RS16005 (HJ580_16020) 3572830..3573303 - 474 WP_012768688.1 DNA repair protein RadC -
HJ580_RS16010 (HJ580_16025) 3573334..3574155 - 822 WP_102802210.1 DUF932 domain-containing protein -
HJ580_RS16015 (HJ580_16030) 3574252..3575118 - 867 WP_102802211.1 GTPase family protein -
HJ580_RS16020 (HJ580_16035) 3575807..3576346 + 540 WP_233788994.1 hypothetical protein -
HJ580_RS16025 (HJ580_16040) 3576350..3577516 + 1167 WP_102802212.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(6-105)

Antitoxin

Antitoxin CbeA

(22-121)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11955.60 Da        Isoelectric Point: 5.0757

>T155762 WP_102802208.1 NZ_CP053013:c3572403-3572083 [Dickeya zeae]
MQTPSPSPAREASSCLSPVNVWQQLLTYLLDKHYGLTLNDTPFCEEAEIQAHLDAGVSLPDAVNFLVERYELVRIDRSGF
SWQEQKPFLNAVDILRARRATGLLKP

Download         Length: 321 bp

>T155762 NZ_CP068814:1298877-1299188 [Escherichia coli]
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTACACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCTAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14770.91 Da        Isoelectric Point: 6.9476

>AT155762 WP_102802209.1 NZ_CP053013:c3572830-3572429 [Dickeya zeae]
MPFTVIPSTCQEKRTLSLSDAPEWGLEHTLRPRFGARLVQEGCRLHFLADRAGVTGTFSATVACHLEHRFPLLVRQLEQK
LVTGELDPYRQQRVTLHDGVLTCEADTLGSAGYVYITIYPTTAATPTTTFPLP

Download         Length: 402 bp

>AT155762 NZ_CP068814:1299185-1299604 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCAGCAATGCCGGTT
GGCGTGGCCTTACTTCGTACGCTGATTGATCAACATAATTTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
TCTGGTCAGTCAGATTTTGTCTGGGCAACGATCCCTGACGATATCCCATATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References