Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 583572..584098 Replicon chromosome
Accession NZ_CP053013
Organism Dickeya zeae strain MS_2014

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag HJ580_RS02630 Protein ID WP_102800987.1
Coordinates 583572..583877 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag HJ580_RS02635 Protein ID WP_102800988.1
Coordinates 583880..584098 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HJ580_RS02610 (HJ580_02610) 579456..579956 + 501 WP_102800984.1 serine acetyltransferase -
HJ580_RS02615 (HJ580_02615) 580064..580357 + 294 WP_038903249.1 DUF1778 domain-containing protein -
HJ580_RS02620 (HJ580_02620) 580354..580842 + 489 WP_102800985.1 GNAT family N-acetyltransferase -
HJ580_RS02625 (HJ580_02625) 581000..583201 + 2202 WP_102800986.1 AAA family ATPase -
HJ580_RS02630 (HJ580_02630) 583572..583877 - 306 WP_102800987.1 type II toxin-antitoxin system toxin CcdB Toxin
HJ580_RS02635 (HJ580_02635) 583880..584098 - 219 WP_102800988.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
HJ580_RS02640 584157..584410 - 254 Protein_513 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
HJ580_RS02650 (HJ580_02645) 584773..585348 - 576 WP_102800989.1 transcriptional regulator -
HJ580_RS02655 (HJ580_02650) 585441..587190 - 1750 Protein_515 protein-disulfide reductase DsbD -
HJ580_RS02660 (HJ580_02655) 587166..587528 - 363 WP_102802664.1 divalent cation tolerance protein CutA -
HJ580_RS02665 (HJ580_02660) 587643..588944 - 1302 WP_019843755.1 anaerobic C4-dicarboxylate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11632.45 Da        Isoelectric Point: 4.6389

>T155748 WP_102800987.1 NZ_CP053013:c583877-583572 [Dickeya zeae]
MQFIVYQYKRASHYKMFIDVQSDIVDTPGRRMVIPLIEAHHLSDKVNKTLFPLIRIEGEDYRLMTTELSSVPVEVVGEAL
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

>T155748 NZ_CP068813:c4481261-4480974 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8148.14 Da        Isoelectric Point: 8.6383

>AT155748 WP_102800988.1 NZ_CP053013:c584098-583880 [Dickeya zeae]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDVIGKEARRIKAEAWKKENREGMEEVARFIAQNGSFADENRNW

Download         Length: 219 bp

>AT155748 NZ_CP068813:c4480987-4480685 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References