Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3399630..3399833 Replicon chromosome
Accession NZ_CP052870
Organism Enterobacter cloacae strain 3849

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3399637..3399740 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3399630..3399833 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HJI43_RS16235 3394635..3395063 + 429 WP_063921947.1 hypothetical protein -
HJI43_RS16240 3395060..3395212 + 153 WP_169441203.1 DUF1317 family protein -
HJI43_RS16245 3395209..3395868 + 660 WP_169441204.1 DNA methyltransferase -
HJI43_RS16250 3395865..3396080 + 216 WP_169441206.1 hypothetical protein -
HJI43_RS16255 3396080..3396376 + 297 WP_169441208.1 DUF4406 domain-containing protein -
HJI43_RS16260 3396373..3396564 + 192 WP_120157928.1 DUF1382 family protein -
HJI43_RS16265 3396656..3396874 + 219 WP_169441209.1 TraR/DksA family transcriptional regulator -
HJI43_RS16270 3396883..3397092 + 210 WP_032677372.1 hypothetical protein -
HJI43_RS16275 3397089..3397538 + 450 WP_072210197.1 DUF2591 family protein -
HJI43_RS16280 3397501..3397740 + 240 Protein_3173 DUF4222 domain-containing protein -
HJI43_RS16285 3397750..3398076 + 327 WP_169441211.1 DUF550 domain-containing protein -
HJI43_RS16290 3398233..3398505 + 273 WP_023300430.1 hypothetical protein -
HJI43_RS16295 3398474..3399559 + 1086 WP_169441213.1 phage integrase Arm DNA-binding domain-containing protein -
- 3399630..3399833 + 204 - - Antitoxin
- 3399637..3399740 - 104 - - Toxin
HJI43_RS16300 3399883..3400221 - 339 WP_022648464.1 YebY family protein -
HJI43_RS16305 3400238..3401107 - 870 WP_046619433.1 copper homeostasis membrane protein CopD -
HJI43_RS16310 3401109..3401480 - 372 WP_023300433.1 CopC domain-containing protein YobA -
HJI43_RS16315 3401618..3401848 + 231 WP_003859784.1 DNA polymerase III subunit theta -
HJI43_RS16320 3401960..3402598 + 639 WP_023300434.1 carbon-nitrogen hydrolase family protein -
HJI43_RS16325 3402623..3403285 + 663 WP_022648468.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrA / gtrB 3335345..3406068 70723


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T155680 NZ_CP052870:c3399740-3399637 [Enterobacter cloacae]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT155680 NZ_CP052870:3399630-3399833 [Enterobacter cloacae]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References