Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 315646..316294 Replicon chromosome
Accession NZ_CP052863
Organism Stenotrophomonas maltophilia strain CF13

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HKK60_RS01340 Protein ID WP_169448014.1
Coordinates 315646..315933 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag HKK60_RS01345 Protein ID WP_169448015.1
Coordinates 315992..316294 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKK60_RS01335 311155..314886 - 3732 WP_169448013.1 hypothetical protein -
HKK60_RS01340 315646..315933 + 288 WP_169448014.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HKK60_RS01345 315992..316294 + 303 WP_169448015.1 putative addiction module antidote protein Antitoxin
HKK60_RS01350 316464..316865 - 402 Protein_268 hypothetical protein -
HKK60_RS01355 317460..318230 + 771 WP_169448016.1 DUF3011 domain-containing protein -
HKK60_RS01360 318255..318601 - 347 Protein_270 hypothetical protein -
HKK60_RS01365 318732..319652 + 921 WP_005407709.1 arginase -
HKK60_RS01370 319813..319950 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
HKK60_RS01375 320159..320380 + 222 WP_004153772.1 CsbD family protein -
HKK60_RS01380 320454..321263 - 810 WP_169448017.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-94)

Antitoxin

Uncharacterized protein HI1420

(8-97)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10710.29 Da        Isoelectric Point: 10.5737

>T155672 WP_169448014.1 NZ_CP052863:315646-315933 [Stenotrophomonas maltophilia]
MKIQRTRQFGTCIDALKDVTGRARILARIGRLSEGHLGDHRYLADGVSELRIDVGPGYRVYYTQRGRQWVILLAGGDKGS
QQRDIEKAKELARAL

Download         Length: 288 bp

>T155672 NZ_CP068811:972365-972772 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10724.42 Da        Isoelectric Point: 10.0074

>AT155672 WP_169448015.1 NZ_CP052863:315992-316294 [Stenotrophomonas maltophilia]
MAIKKKVELKAFDVAEHLRTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLRASAA

Download         Length: 303 bp

>AT155672 NZ_CP068811:972118-972384 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGATGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References