Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4277945..4278461 Replicon chromosome
Accession NZ_CP052862
Organism Pseudomonas sp. ADAK2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HKK52_RS19675 Protein ID WP_169372203.1
Coordinates 4277945..4278226 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HKK52_RS19680 Protein ID WP_133840022.1
Coordinates 4278216..4278461 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKK52_RS19650 4273968..4274855 - 888 WP_123516005.1 HlyD family secretion protein -
HKK52_RS19655 4274852..4275061 - 210 WP_054050271.1 DUF1656 domain-containing protein -
HKK52_RS19660 4275058..4277130 - 2073 WP_169372200.1 FUSC family protein -
HKK52_RS19665 4277127..4277555 - 429 WP_169372201.1 winged helix DNA-binding protein -
HKK52_RS19670 4277751..4277948 + 198 WP_169372202.1 hypothetical protein -
HKK52_RS19675 4277945..4278226 - 282 WP_169372203.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HKK52_RS19680 4278216..4278461 - 246 WP_133840022.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HKK52_RS19685 4278608..4278853 - 246 WP_133840021.1 DUF2789 domain-containing protein -
HKK52_RS19690 4278972..4279433 - 462 WP_169372204.1 YbaK/EbsC family protein -
HKK52_RS19695 4279630..4280163 + 534 WP_169372205.1 serine protease -
HKK52_RS19700 4280166..4280924 + 759 WP_169372206.1 slipin family protein -
HKK52_RS19705 4280905..4281186 + 282 WP_169374267.1 hypothetical protein -
HKK52_RS19710 4281277..4281618 + 342 WP_178117460.1 hypothetical protein -
HKK52_RS19715 4281709..4282050 + 342 WP_169372207.1 hypothetical protein -
HKK52_RS19720 4282099..4283052 - 954 WP_169372208.1 sulfotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10935.77 Da        Isoelectric Point: 10.3662

>T155668 WP_169372203.1 NZ_CP052862:c4278226-4277945 [Pseudomonas sp. ADAK2]
MTYKLEFLPSARKEWDKLGHTLREQFKKKLAERLELPRVPSDSLHGMPDCYKIKLRSAGYRLVYEVIDERVVVSVVAVGK
RERSAVYDRAKQR

Download         Length: 282 bp

>T155668 NZ_CP068811:263946-264053 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8907.23 Da        Isoelectric Point: 4.7124

>AT155668 WP_133840022.1 NZ_CP052862:c4278461-4278216 [Pseudomonas sp. ADAK2]
MQNVLADIAVSVSELKKNPSAVLNGAHGGPVAVLNHNRVMGYMVPADVFESMMERLDDLELAEIVRSRRHETPIPVNLDD
L

Download         Length: 246 bp

>AT155668 NZ_CP068811:c263897-263834 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References