Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 3938990..3939621 Replicon chromosome
Accession NZ_CP052862
Organism Pseudomonas sp. ADAK2

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HKK52_RS18085 Protein ID WP_169371957.1
Coordinates 3938990..3939352 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HKK52_RS18090 Protein ID WP_169371958.1
Coordinates 3939352..3939621 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKK52_RS18075 3934091..3937471 + 3381 WP_169371955.1 mechanosensitive channel MscK -
HKK52_RS18080 3937520..3938983 + 1464 WP_169371956.1 YdiU family protein -
HKK52_RS18085 3938990..3939352 - 363 WP_169371957.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
HKK52_RS18090 3939352..3939621 - 270 WP_169371958.1 PbsX family transcriptional regulator Antitoxin
HKK52_RS18095 3939892..3940326 + 435 WP_169371959.1 thioredoxin TrxC -
HKK52_RS18100 3940453..3941223 - 771 WP_054053184.1 ParA family protein -
HKK52_RS18105 3941580..3942305 + 726 WP_169374260.1 beta-ketoacyl synthase chain length factor -
HKK52_RS18110 3942281..3943090 + 810 WP_169371960.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
HKK52_RS18115 3943071..3943331 + 261 WP_169371961.1 acyl carrier protein -
HKK52_RS18120 3943341..3943595 + 255 WP_007992314.1 acyl carrier protein -
HKK52_RS18125 3943592..3944137 + 546 WP_169371962.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13164.05 Da        Isoelectric Point: 8.0621

>T155667 WP_169371957.1 NZ_CP052862:c3939352-3938990 [Pseudomonas sp. ADAK2]
MVRRQAPQRGDVFWIDPNPVAGREMMNRHRFVVITPRGINALGVSMTVPVTSGGSFSRNSGLAVVVTGHETNGVAVCNQV
RSFDIEQRVREGSAKFIERLDDVTMTDIIARVVSAIDPLD

Download         Length: 363 bp

>T155667 NZ_CP068811:263462-263569 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9692.11 Da        Isoelectric Point: 5.1316

>AT155667 WP_169371958.1 NZ_CP052862:c3939621-3939352 [Pseudomonas sp. ADAK2]
MSVTSKIRRQGGAAVITLPPTLLKLLHLEVGSQLELNVVDGELIARPVVKASRKRYSLDELLQGAEELAELNEQTAWARE
GDSVGRELG

Download         Length: 270 bp

>AT155667 NZ_CP068811:c263404-263350 [Escherichia coli]
CAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References