Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5724675..5725180 Replicon chromosome
Accession NZ_CP052861
Organism Pseudomonas sp. ADAK7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HKK53_RS26365 Protein ID WP_123410195.1
Coordinates 5724675..5724929 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HKK53_RS26370 Protein ID WP_123410196.1
Coordinates 5724926..5725180 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKK53_RS26335 5719766..5720473 + 708 WP_169373181.1 peptide-methionine (S)-S-oxide reductase MsrA -
HKK53_RS26340 5720468..5720950 - 483 WP_169373182.1 GNAT family N-acetyltransferase -
HKK53_RS26345 5720995..5721399 - 405 WP_169373183.1 GNAT family N-acetyltransferase -
HKK53_RS26350 5721396..5722409 - 1014 WP_169373184.1 sensor domain-containing diguanylate cyclase -
HKK53_RS26355 5722485..5723390 - 906 WP_169373185.1 LysR family transcriptional regulator -
HKK53_RS26360 5723493..5724668 + 1176 WP_169373186.1 aspartate aminotransferase family protein -
HKK53_RS26365 5724675..5724929 - 255 WP_123410195.1 Txe/YoeB family addiction module toxin Toxin
HKK53_RS26370 5724926..5725180 - 255 WP_123410196.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HKK53_RS26375 5725380..5725964 - 585 WP_169373187.1 DedA family protein -
HKK53_RS26380 5725949..5726374 - 426 WP_169373188.1 VOC family protein -
HKK53_RS26385 5726388..5726903 - 516 WP_169373189.1 adenylate kinase -
HKK53_RS26390 5726912..5728813 - 1902 WP_169373190.1 alkaline phosphatase family protein -
HKK53_RS26395 5729115..5729906 - 792 WP_169373191.1 VacJ family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9966.44 Da        Isoelectric Point: 8.9271

>T155664 WP_123410195.1 NZ_CP052861:c5724929-5724675 [Pseudomonas sp. ADAK7]
MNIEFTTEGWNDYLWFQQNDKAGLKRINLLIKAIQREPFSGPGKPEPLKHNLSGFWSRRITTEHRLVYAIEEGAIQIVMC
RYHY

Download         Length: 255 bp

>T155664 NZ_CP068810:c5076915-5076604 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTGTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9442.86 Da        Isoelectric Point: 8.5163

>AT155664 WP_123410196.1 NZ_CP052861:c5725180-5724926 [Pseudomonas sp. ADAK7]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKAKARQ
LIEE

Download         Length: 255 bp

>AT155664 NZ_CP068810:c5076603-5076313 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACACCCTTC
ACGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGAAC
TTATTTCCGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACTGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAGGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References