Detailed information of TA system TA155662

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4277947..4278463
• Replicon: chromosome
• Accession: NZ_CP052861
• Organism: Pseudomonas sp. ADAK7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HKK53_RS19680
• Protein ID: WP_169372203.1
• Coordinates: 4277947..4278228 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HKK53_RS19685
• Protein ID: WP_133840022.1
• Coordinates: 4278218..4278463 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HKK53_RS19655	4273970..4274857	-	888	WP_123516005.1	HlyD family secretion protein	-
HKK53_RS19660	4274854..4275063	-	210	WP_054050271.1	DUF1656 domain-containing protein	-
HKK53_RS19665	4275060..4277132	-	2073	WP_169372200.1	FUSC family protein	-
HKK53_RS19670	4277129..4277557	-	429	WP_169372201.1	winged helix DNA-binding protein	-
HKK53_RS19675	4277753..4277950	+	198	WP_169372202.1	hypothetical protein	-
HKK53_RS19680	4277947..4278228	-	282	WP_169372203.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HKK53_RS19685	4278218..4278463	-	246	WP_133840022.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HKK53_RS19690	4278610..4278855	-	246	WP_133840021.1	DUF2789 domain-containing protein	-
HKK53_RS19695	4278974..4279435	-	462	WP_169372204.1	YbaK/EbsC family protein	-
HKK53_RS19700	4279632..4280165	+	534	WP_169372205.1	serine protease	-
HKK53_RS19705	4280168..4280926	+	759	WP_169372206.1	slipin family protein	-
HKK53_RS19710	4280907..4281188	+	282	WP_169374267.1	hypothetical protein	-
HKK53_RS19715	4281279..4281620	+	342	WP_178117460.1	hypothetical protein	-
HKK53_RS19720	4281711..4282052	+	342	WP_169372207.1	hypothetical protein	-
HKK53_RS19725	4282101..4283054	-	954	WP_169372208.1	sulfotransferase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-69)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10935.77 Da
• Isoelectric Point: 10.3662

>T155662 WP_169372203.1 NZ_CP052861:c4278228-4277947 [Pseudomonas sp. ADAK7]
MTYKLEFLPSARKEWDKLGHTLREQFKKKLAERLELPRVPSDSLHGMPDCYKIKLRSAGYRLVYEVIDERVVVSVVAVGK
RERSAVYDRAKQR

Nucleotide

• Length: 282 bp

>T155662 NZ_CP068810:c4683838-4683488 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGTGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8907.23 Da
• Isoelectric Point: 4.7124

>AT155662 WP_133840022.1 NZ_CP052861:c4278463-4278218 [Pseudomonas sp. ADAK7]
MQNVLADIAVSVSELKKNPSAVLNGAHGGPVAVLNHNRVMGYMVPADVFESMMERLDDLELAEIVRSRRHETPIPVNLDD
L

Nucleotide

• Length: 246 bp

>AT155662 NZ_CP068810:c4684083-4683832 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA