Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4277947..4278463 Replicon chromosome
Accession NZ_CP052861
Organism Pseudomonas sp. ADAK7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HKK53_RS19680 Protein ID WP_169372203.1
Coordinates 4277947..4278228 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HKK53_RS19685 Protein ID WP_133840022.1
Coordinates 4278218..4278463 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKK53_RS19655 4273970..4274857 - 888 WP_123516005.1 HlyD family secretion protein -
HKK53_RS19660 4274854..4275063 - 210 WP_054050271.1 DUF1656 domain-containing protein -
HKK53_RS19665 4275060..4277132 - 2073 WP_169372200.1 FUSC family protein -
HKK53_RS19670 4277129..4277557 - 429 WP_169372201.1 winged helix DNA-binding protein -
HKK53_RS19675 4277753..4277950 + 198 WP_169372202.1 hypothetical protein -
HKK53_RS19680 4277947..4278228 - 282 WP_169372203.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HKK53_RS19685 4278218..4278463 - 246 WP_133840022.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HKK53_RS19690 4278610..4278855 - 246 WP_133840021.1 DUF2789 domain-containing protein -
HKK53_RS19695 4278974..4279435 - 462 WP_169372204.1 YbaK/EbsC family protein -
HKK53_RS19700 4279632..4280165 + 534 WP_169372205.1 serine protease -
HKK53_RS19705 4280168..4280926 + 759 WP_169372206.1 slipin family protein -
HKK53_RS19710 4280907..4281188 + 282 WP_169374267.1 hypothetical protein -
HKK53_RS19715 4281279..4281620 + 342 WP_178117460.1 hypothetical protein -
HKK53_RS19720 4281711..4282052 + 342 WP_169372207.1 hypothetical protein -
HKK53_RS19725 4282101..4283054 - 954 WP_169372208.1 sulfotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10935.77 Da        Isoelectric Point: 10.3662

>T155662 WP_169372203.1 NZ_CP052861:c4278228-4277947 [Pseudomonas sp. ADAK7]
MTYKLEFLPSARKEWDKLGHTLREQFKKKLAERLELPRVPSDSLHGMPDCYKIKLRSAGYRLVYEVIDERVVVSVVAVGK
RERSAVYDRAKQR

Download         Length: 282 bp

>T155662 NZ_CP068810:c4683838-4683488 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGTGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8907.23 Da        Isoelectric Point: 4.7124

>AT155662 WP_133840022.1 NZ_CP052861:c4278463-4278218 [Pseudomonas sp. ADAK7]
MQNVLADIAVSVSELKKNPSAVLNGAHGGPVAVLNHNRVMGYMVPADVFESMMERLDDLELAEIVRSRRHETPIPVNLDD
L

Download         Length: 246 bp

>AT155662 NZ_CP068810:c4684083-4683832 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References