Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 3938992..3939623 Replicon chromosome
Accession NZ_CP052861
Organism Pseudomonas sp. ADAK7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HKK53_RS18090 Protein ID WP_169371957.1
Coordinates 3938992..3939354 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HKK53_RS18095 Protein ID WP_169371958.1
Coordinates 3939354..3939623 (-) Length 90 a.a.

Genomic Context

HKK53_RS18080HKK53_RS18085HKK53_RS18100HKK53_RS18110HKK53_RS18115HKK53_RS18120HKK53_RS18125HKK53_RS18130HKK53_RS18090HKK53_RS18095HKK53_RS18105
Location: 3934093..3937473 (3381 bp)
Type: Others
Protein ID: WP_169371955.1
Location: 3937522..3938985 (1464 bp)
Type: Others
Protein ID: WP_169371956.1
Location: 3939894..3940328 (435 bp)
Type: Others
Protein ID: WP_169371959.1
Location: 3941582..3942307 (726 bp)
Type: Others
Protein ID: WP_169374260.1
Location: 3942283..3943092 (810 bp)
Type: Others
Protein ID: WP_169371960.1
Location: 3943073..3943333 (261 bp)
Type: Others
Protein ID: WP_169371961.1
Location: 3943343..3943597 (255 bp)
Type: Others
Protein ID: WP_007992314.1
Location: 3943594..3944139 (546 bp)
Type: Others
Protein ID: WP_169371962.1
Location: 3938992..3939354 (363 bp)
Type: Toxin
Protein ID: WP_169371957.1
Location: 3939354..3939623 (270 bp)
Type: Antitoxin
Protein ID: WP_169371958.1
Location: 3940455..3941225 (771 bp)
Type: Others
Protein ID: WP_054053184.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HKK53_RS180803934093..3937473+3381WP_169371955.1mechanosensitive channel MscK-
HKK53_RS180853937522..3938985+1464WP_169371956.1YdiU family protein-
HKK53_RS180903938992..3939354-363WP_169371957.1type II toxin-antitoxin system PemK/MazF family toxinToxin
HKK53_RS180953939354..3939623-270WP_169371958.1PbsX family transcriptional regulatorAntitoxin
HKK53_RS181003939894..3940328+435WP_169371959.1thioredoxin TrxC-
HKK53_RS181053940455..3941225-771WP_054053184.1ParA family protein-
HKK53_RS181103941582..3942307+726WP_169374260.1beta-ketoacyl synthase chain length factor-
HKK53_RS181153942283..3943092+810WP_169371960.11-acyl-sn-glycerol-3-phosphate acyltransferase-
HKK53_RS181203943073..3943333+261WP_169371961.1acyl carrier protein-
HKK53_RS181253943343..3943597+255WP_007992314.1acyl carrier protein-
HKK53_RS181303943594..3944139+546WP_169371962.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13164.05 Da        Isoelectric Point: 8.0621

>T155661 WP_169371957.1 NZ_CP052861:c3939354-3938992 [Pseudomonas sp. ADAK7]
MVRRQAPQRGDVFWIDPNPVAGREMMNRHRFVVITPRGINALGVSMTVPVTSGGSFSRNSGLAVVVTGHETNGVAVCNQV
RSFDIEQRVREGSAKFIERLDDVTMTDIIARVVSAIDPLD

Download         Length: 363 bp

>T155661 NZ_CP068810:c4672116-4671826 [Escherichia coli]
ATGAACTATGAGCTGGCGTTTGATCCGCGGGCGCTGAAAGAGTGGCAAAAACTGGGCGTGACAGTCCGGGAACAATTTAA
AAAAAAGCTTGAGGATGTGCTGAAAAGGCCGCGCAATCCATCGGCTAAACTGCGGGATTTACCGGACTGCTACAAAATTA
AGCTGCGCACACAGGGATATCGCCTGGTTTATCAGGTTAACGATAAAGAGTTGCTCGTGTTGGTGATAGCTATTGGTAAG
AGAGAGAACTCAGCCGTTTATGAAGACGCGACTAAACGGCTGGATGAGTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9692.11 Da        Isoelectric Point: 5.1316

>AT155661 WP_169371958.1 NZ_CP052861:c3939623-3939354 [Pseudomonas sp. ADAK7]
MSVTSKIRRQGGAAVITLPPTLLKLLHLEVGSQLELNVVDGELIARPVVKASRKRYSLDELLQGAEELAELNEQTAWARE
GDSVGRELG

Download         Length: 270 bp

>AT155661 NZ_CP068810:c4672348-4672106 [Escherichia coli]
ATGGCCACACTTAACGTCCGCCTGGATGACAAACTGAAAAATGAGGCTTATGCGGTGCTGGAAAAATTAAATATCACGCC
TACTGAAGCAGTGCGGCTGCTGTTTCAGTACGTTGCGGAAAATGGACGAATGCCGGTAAAAACGCTCACTGTCAGTGATA
GTGAAGAAGCCTTGTTACGCACTGTCAGGGAACGACTGGCCAACCCACAAGAGGCCATTAAGGTCCGACTGGATGAACTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References