Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5253054..5253570 Replicon chromosome
Accession NZ_CP052859
Organism Pseudomonas sp. ADAK18

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HKK55_RS23855 Protein ID WP_169356851.1
Coordinates 5253054..5253341 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HKK55_RS23860 Protein ID WP_169356852.1
Coordinates 5253331..5253570 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKK55_RS23840 5248362..5250203 + 1842 WP_169356848.1 dihydroxy-acid dehydratase -
HKK55_RS23845 5250329..5251369 - 1041 WP_178128896.1 haloacid dehalogenase-like hydrolase -
HKK55_RS23850 5251627..5253018 + 1392 WP_169356850.1 L-cystine transporter -
HKK55_RS23855 5253054..5253341 - 288 WP_169356851.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HKK55_RS23860 5253331..5253570 - 240 WP_169356852.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HKK55_RS23865 5253654..5254166 - 513 WP_169356853.1 dihydrofolate reductase -
HKK55_RS23870 5254257..5255636 + 1380 WP_169356854.1 DUF2868 domain-containing protein -
HKK55_RS23875 5255629..5257002 + 1374 WP_169356855.1 DUF3482 domain-containing protein -
HKK55_RS23880 5256999..5257553 - 555 WP_169356856.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11335.11 Da        Isoelectric Point: 9.9161

>T155654 WP_169356851.1 NZ_CP052859:c5253341-5253054 [Pseudomonas sp. ADAK18]
MTYNLEFDARSLKEWHKLGDTVRQQFKKKLVEILIQPRIEANRLHGLPDCYKIKLHSSGYRLVYQVIDQEVTVFVVAVNK
RERDEVYRKATDRLS

Download         Length: 288 bp

>T155654 NZ_CP068810:3214868-3215362 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.8096

>AT155654 WP_169356852.1 NZ_CP052859:c5253570-5253331 [Pseudomonas sp. ADAK18]
MASINVRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT155654 NZ_CP068810:3214578-3214871 [Escherichia coli]
ATGCCAGCAGCCAATAACATTCCAACCAGGCGCGAATCTTTAAATTTGCGCATAAAACCCGCAGAACGCGATCTTATTGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCACCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCAGCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References