Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2502387..2503070 Replicon chromosome
Accession NZ_CP052855
Organism Xylella fastidiosa subsp. multiplex strain Fillmore

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HKJ31_RS11160 Protein ID WP_004086858.1
Coordinates 2502387..2502815 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HKJ31_RS11165 Protein ID WP_004086856.1
Coordinates 2502816..2503070 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKJ31_RS11130 2498941..2499702 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
HKJ31_RS11155 2500903..2502297 + 1395 WP_169710402.1 hypothetical protein -
HKJ31_RS11160 2502387..2502815 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
HKJ31_RS11165 2502816..2503070 - 255 WP_004086856.1 hypothetical protein Antitoxin
HKJ31_RS11170 2503195..2503737 + 543 WP_004086854.1 hypothetical protein -
HKJ31_RS11175 2504058..2504431 - 374 Protein_2178 DUF596 domain-containing protein -
HKJ31_RS11180 2504443..2504775 - 333 WP_076613248.1 DUF769 domain-containing protein -
HKJ31_RS11185 2504947..2505339 - 393 WP_038211775.1 DUF596 domain-containing protein -
HKJ31_RS11190 2505350..2505703 - 354 Protein_2181 DUF769 domain-containing protein -
HKJ31_RS11195 2505881..2506264 - 384 WP_004086848.1 DUF596 domain-containing protein -
HKJ31_RS11200 2506269..2507306 - 1038 WP_004086846.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T155635 WP_004086858.1 NZ_CP052855:c2502815-2502387 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T155635 NZ_CP068809:c4379258-4378881 [Escherichia coli]
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT155635 WP_004086856.1 NZ_CP052855:c2503070-2502816 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT155635 NZ_CP068809:c4379716-4379348 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References