Detailed information of TA system TA155632

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 1115008..1115762
• Replicon: chromosome
• Accession: NZ_CP052855
• Organism: Xylella fastidiosa subsp. multiplex strain Fillmore

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: HKJ31_RS05050
• Protein ID: WP_021358673.1
• Coordinates: 1115008..1115487 (-)
• Length: 160 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: HKJ31_RS05055
• Protein ID: WP_004085396.1
• Coordinates: 1115490..1115762 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HKJ31_RS05040	1111861..1112667	+	807	WP_038211175.1	oxidoreductase	-
HKJ31_RS05045	1112807..1114672	+	1866	WP_020852085.1	toprim domain-containing protein	-
HKJ31_RS05050	1115008..1115487	-	480	WP_021358673.1	GNAT family N-acetyltransferase	Toxin
HKJ31_RS05055	1115490..1115762	-	273	WP_004085396.1	DUF1778 domain-containing protein	Antitoxin
HKJ31_RS05060	1116114..1117019	-	906	WP_004085395.1	AEC family transporter	-
HKJ31_RS05065	1117135..1117753	+	619	Protein_982	IS607 family transposase	-
HKJ31_RS05070	1117948..1120016	+	2069	Protein_983	glycoside hydrolase family 3 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (33-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (3-85)

Sequences

Toxin

Protein

• Length: 160 a.a.
• Molecular weight: 17645.42 Da
• Isoelectric Point: 9.9283

>T155632 WP_021358673.1 NZ_CP052855:c1115487-1115008 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Nucleotide

• Length: 480 bp

>T155632 NZ_CP068809:c4178887-4178573 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10264.77 Da
• Isoelectric Point: 5.0488

>AT155632 WP_004085396.1 NZ_CP052855:c1115762-1115490 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Nucleotide

• Length: 273 bp

>AT155632 NZ_CP068809:c4179123-4178890 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACA
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG