Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 704751..705547 | Replicon | chromosome |
| Accession | NZ_CP052855 | ||
| Organism | Xylella fastidiosa subsp. multiplex strain Fillmore | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | - |
| Locus tag | HKJ31_RS03185 | Protein ID | WP_004087040.1 |
| Coordinates | 704751..705362 (-) | Length | 204 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | A0A060HF63 |
| Locus tag | HKJ31_RS03190 | Protein ID | WP_004087046.1 |
| Coordinates | 705359..705547 (-) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HKJ31_RS03135 | 699959..700237 | - | 279 | WP_004086925.1 | hypothetical protein | - |
| HKJ31_RS03140 | 700216..701328 | - | 1113 | WP_004086911.1 | Bro-N domain-containing protein | - |
| HKJ31_RS03145 | 701358..702146 | - | 789 | WP_169710410.1 | Bro-N domain-containing protein | - |
| HKJ31_RS03150 | 702150..702455 | - | 306 | Protein_606 | hypothetical protein | - |
| HKJ31_RS03155 | 702404..702769 | - | 366 | WP_169710333.1 | hypothetical protein | - |
| HKJ31_RS03160 | 702766..703014 | - | 249 | WP_038231490.1 | hypothetical protein | - |
| HKJ31_RS03165 | 703011..703199 | - | 189 | WP_020851634.1 | hypothetical protein | - |
| HKJ31_RS03170 | 703227..703418 | - | 192 | WP_154128206.1 | hypothetical protein | - |
| HKJ31_RS03175 | 703677..703922 | - | 246 | WP_038211690.1 | hypothetical protein | - |
| HKJ31_RS03180 | 704278..704700 | + | 423 | Protein_612 | peptidase | - |
| HKJ31_RS03185 | 704751..705362 | - | 612 | WP_004087040.1 | Fic/DOC family protein | Toxin |
| HKJ31_RS03190 | 705359..705547 | - | 189 | WP_004087046.1 | antitoxin VbhA family protein | Antitoxin |
| HKJ31_RS03195 | 705928..706383 | + | 456 | WP_004086362.1 | hypothetical protein | - |
| HKJ31_RS03200 | 706494..706931 | + | 438 | WP_038231390.1 | hypothetical protein | - |
| HKJ31_RS03205 | 706928..707398 | + | 471 | WP_027700621.1 | DUF1566 domain-containing protein | - |
| HKJ31_RS03210 | 707395..707802 | + | 408 | WP_154437007.1 | hypothetical protein | - |
| HKJ31_RS03215 | 707799..707990 | + | 192 | WP_004086069.1 | hypothetical protein | - |
| HKJ31_RS03220 | 708034..708561 | + | 528 | WP_169710335.1 | hypothetical protein | - |
| HKJ31_RS03225 | 708680..708871 | + | 192 | WP_154128433.1 | hypothetical protein | - |
| HKJ31_RS03230 | 708892..709254 | + | 363 | WP_004086369.1 | hypothetical protein | - |
| HKJ31_RS03235 | 709276..710097 | + | 822 | WP_154128435.1 | DUF2303 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 672247..718420 | 46173 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22961.76 Da Isoelectric Point: 5.1271
>T155631 WP_004087040.1 NZ_CP052855:c705362-704751 [Xylella fastidiosa subsp. multiplex]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
>T155631 NZ_CP068809:c3925469-3925071 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGAAGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGTGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGCAGCGCATTTGGTATATTGTCAGGGCGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGAAGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGTGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGCAGCGCATTTGGTATATTGTCAGGGCGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6855.80 Da Isoelectric Point: 4.9859
>AT155631 WP_004087046.1 NZ_CP052855:c705547-705359 [Xylella fastidiosa subsp. multiplex]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
Download Length: 189 bp
>AT155631 NZ_CP068809:c3925765-3925472 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
TGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTTGAAGCATTAATGGACATGCTTG
CAGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCGAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
TGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTTGAAGCATTAATGGACATGCTTG
CAGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCGAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|