Detailed information of TA system TA155622

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 1115625..1116379
• Replicon: chromosome
• Accession: NZ_CP052854
• Organism: Xylella fastidiosa subsp. multiplex strain LM10

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: HKJ32_RS04935
• Protein ID: WP_021358673.1
• Coordinates: 1115625..1116104 (-)
• Length: 160 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: HKJ32_RS04940
• Protein ID: WP_004085396.1
• Coordinates: 1116107..1116379 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HKJ32_RS04925	1112480..1113286	+	807	WP_038211175.1	oxidoreductase	-
HKJ32_RS04930	1114320..1115289	+	970	Protein_962	toprim domain-containing protein	-
HKJ32_RS04935	1115625..1116104	-	480	WP_021358673.1	GNAT family N-acetyltransferase	Toxin
HKJ32_RS04940	1116107..1116379	-	273	WP_004085396.1	DUF1778 domain-containing protein	Antitoxin
HKJ32_RS04945	1116731..1117636	-	906	WP_004085395.1	AEC family transporter	-
HKJ32_RS04950	1117752..1118370	+	619	Protein_966	IS607 family transposase	-
HKJ32_RS04955	1118565..1120631	+	2067	WP_004085393.1	glycosyl hydrolase family 3	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (33-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (3-85)

Sequences

Toxin

Protein

• Length: 160 a.a.
• Molecular weight: 17645.42 Da
• Isoelectric Point: 9.9283

>T155622 WP_021358673.1 NZ_CP052854:c1116104-1115625 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Nucleotide

• Length: 480 bp

>T155622 NZ_CP068809:2228822-2228924 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10264.77 Da
• Isoelectric Point: 5.0488

>AT155622 WP_004085396.1 NZ_CP052854:c1116379-1116107 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Nucleotide

• Length: 273 bp

>AT155622 NZ_CP068809:c2228962-2228694 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT