Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2652512..2653195 Replicon chromosome
Accession NZ_CP052853
Organism Xylella fastidiosa subsp. multiplex strain RH1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HKJ33_RS12105 Protein ID WP_004086858.1
Coordinates 2652512..2652940 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HKJ33_RS12110 Protein ID WP_004086856.1
Coordinates 2652941..2653195 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKJ33_RS12070 2649066..2649827 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
HKJ33_RS12095 2650640..2650792 + 153 WP_169710102.1 hypothetical protein -
HKJ33_RS12100 2651028..2652422 + 1395 WP_169710103.1 hypothetical protein -
HKJ33_RS12105 2652512..2652940 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
HKJ33_RS12110 2652941..2653195 - 255 WP_004086856.1 hypothetical protein Antitoxin
HKJ33_RS12115 2653320..2653862 + 543 WP_004086854.1 hypothetical protein -
HKJ33_RS12120 2653874..2654017 + 144 WP_169710104.1 hypothetical protein -
HKJ33_RS12125 2654183..2654556 - 374 Protein_2370 DUF596 domain-containing protein -
HKJ33_RS12130 2654568..2654900 - 333 WP_076613248.1 DUF769 domain-containing protein -
HKJ33_RS12135 2655072..2655464 - 393 WP_038211775.1 DUF596 domain-containing protein -
HKJ33_RS12140 2655475..2655828 - 354 Protein_2373 DUF769 domain-containing protein -
HKJ33_RS12145 2656006..2656389 - 384 WP_004086848.1 DUF596 domain-containing protein -
HKJ33_RS12150 2656394..2657431 - 1038 WP_169710105.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T155618 WP_004086858.1 NZ_CP052853:c2652940-2652512 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T155618 NZ_CP068809:1129627-1129962 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATACGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTCTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGA
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT155618 WP_004086856.1 NZ_CP052853:c2653195-2652941 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT155618 NZ_CP068809:1129379-1129627 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGGGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References