155583

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4212183..4212733 Replicon chromosome
Accession NZ_CP052766
Organism Alteromonas pelagimontana strain 5.12

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CA267_RS18480 Protein ID WP_075609424.1
Coordinates 4212183..4212473 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CA267_RS18485 Protein ID WP_075609423.1
Coordinates 4212461..4212733 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA267_RS18465 4207494..4208510 - 1017 Protein_3619 FAD:protein FMN transferase -
CA267_RS18470 4208535..4209334 - 800 Protein_3620 undecaprenyl-diphosphate phosphatase -
CA267_RS18475 4209417..4212176 - 2760 Protein_3621 Tn3 family transposase -
CA267_RS18480 4212183..4212473 - 291 WP_075609424.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CA267_RS18485 4212461..4212733 - 273 WP_075609423.1 CopG family ribbon-helix-helix protein Antitoxin
CA267_RS18490 4213038..4213598 + 561 WP_075609422.1 recombinase family protein -
CA267_RS18495 4214198..4215427 + 1230 WP_075609420.1 spore maturation protein -
CA267_RS18500 4215529..4216227 + 699 WP_075609419.1 SIMPL domain-containing protein -
CA267_RS18505 4216315..4216692 + 378 WP_083638544.1 GAF domain-containing protein -
CA267_RS18510 4216689..4216979 + 291 WP_075609417.1 hypothetical protein -
CA267_RS18515 4216997..4217665 + 669 WP_075609416.1 RNA chaperone ProQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10895.54 Da        Isoelectric Point: 8.4845

>T155583 WP_075609424.1 NZ_CP052766:c4212473-4212183 [Alteromonas pelagimontana]
VPRLIWSPSALADVQRLYRFLAIKDEDAARRAIKTIRAGVKILAHQPEAGRPVEDMEPVFREWPIDFGTSGYVALYRFDG
ETAIILAVRHQKEAGY

Download         Length: 291 bp

>T155583 NZ_CP068807:c5347290-5347183 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10716.90 Da        Isoelectric Point: 5.0000

>AT155583 WP_075609423.1 NZ_CP052766:c4212733-4212461 [Alteromonas pelagimontana]
MATSVKLDENLKGRIQHLAEVRHRSSHWIMREAIREYVEREEKRESFKQDALRAWESYQENGQHLTLEEADAWLEKLEAG
DDVELPKCHD

Download         Length: 273 bp

>AT155583 NZ_CP068807:5347337-5347403 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References