155563

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1168403..1169061 Replicon chromosome
Accession NZ_CP052761
Organism Klebsiella pneumoniae strain XH210

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag RJ97_RS05820 Protein ID WP_038434453.1
Coordinates 1168403..1168723 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag RJ97_RS05825 Protein ID WP_038434454.1
Coordinates 1168744..1169061 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RJ97_RS05800 (1164798) 1164798..1165763 - 966 WP_023301570.1 retron St85 family RNA-directed DNA polymerase -
RJ97_RS05805 (1166189) 1166189..1166830 - 642 WP_023301571.1 hypothetical protein -
RJ97_RS26735 (1166832) 1166832..1168078 - 1247 Protein_1138 integrase domain-containing protein -
RJ97_RS05820 (1168403) 1168403..1168723 - 321 WP_038434453.1 TA system toxin CbtA family protein Toxin
RJ97_RS05825 (1168744) 1168744..1169061 - 318 WP_038434454.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
RJ97_RS05830 (1169079) 1169079..1169300 - 222 WP_038434455.1 DUF987 domain-containing protein -
RJ97_RS05835 (1169309) 1169309..1169791 - 483 WP_038434456.1 DNA repair protein RadC -
RJ97_RS05840 (1169800) 1169800..1170258 - 459 WP_038434458.1 antirestriction protein -
RJ97_RS05845 (1170344) 1170344..1170580 - 237 WP_038434459.1 DUF905 domain-containing protein -
RJ97_RS05850 (1170658) 1170658..1171068 - 411 WP_038434460.1 hypothetical protein -
RJ97_RS05855 (1171135) 1171135..1171572 - 438 WP_038434461.1 hypothetical protein -
RJ97_RS05860 (1171614) 1171614..1172150 - 537 WP_038434462.1 DUF4339 domain-containing protein -
RJ97_RS05865 (1172176) 1172176..1172886 - 711 WP_038434463.1 DeoR family transcriptional regulator -
RJ97_RS05870 (1173095) 1173095..1173919 - 825 WP_038434464.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1153914..1191506 37592


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-102)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12113.24 Da        Isoelectric Point: 9.7207

>T155563 WP_038434453.1 NZ_CP052761:c1168723-1168403 [Klebsiella pneumoniae]
MKTLPAIISRAAKPCLSPVAVWQMLLTRLLRQHYGLTLNDTPFSNETVIKEHIDAGISLVDAVNFLVEKYELVRIDSKGF
SWQEQSPFITAVDILKARRAMREMRI

Download         Length: 321 bp

>T155563 NZ_CP068807:2276606-2277070 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTACAGCGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAGCCCATTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11761.34 Da        Isoelectric Point: 6.9362

>AT155563 WP_038434454.1 NZ_CP052761:c1169061-1168744 [Klebsiella pneumoniae]
MSNTTWGLQRDITPCLGARLVQEGNRLHYLDDRASITGKFSDAQCIKLNVVFPHFISQIESVLTTGELNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp

>AT155563 NZ_CP068807:2276271-2276606 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCGACACTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References