Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 1965356..1965950 | Replicon | chromosome |
Accession | NZ_CP052116 | ||
Organism | Ralstonia solanacearum strain FJAT1463.F1 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | G3A6N4 |
Locus tag | HI799_RS09535 | Protein ID | WP_016721901.1 |
Coordinates | 1965687..1965950 (-) | Length | 88 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | HI799_RS09530 | Protein ID | WP_038961924.1 |
Coordinates | 1965356..1965694 (-) | Length | 113 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HI799_RS09500 | 1961738..1962076 | + | 339 | WP_016721894.1 | phage tail protein | - |
HI799_RS09505 | 1962073..1962750 | + | 678 | WP_016721895.1 | phage tail protein | - |
HI799_RS09510 | 1962756..1963352 | + | 597 | WP_016721896.1 | tail fiber assembly protein | - |
HI799_RS09515 | 1963349..1964050 | + | 702 | WP_071895496.1 | phage minor tail protein L | - |
HI799_RS09520 | 1964052..1964762 | + | 711 | WP_071895497.1 | C40 family peptidase | - |
HI799_RS09525 | 1964766..1965359 | + | 594 | WP_016721899.1 | tail assembly protein | - |
HI799_RS09530 | 1965356..1965694 | - | 339 | WP_038961924.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
HI799_RS09535 | 1965687..1965950 | - | 264 | WP_016721901.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
HI799_RS09540 | 1966003..1969158 | + | 3156 | WP_016721902.1 | host specificity protein J | - |
HI799_RS09545 | 1969495..1970151 | + | 657 | WP_038961925.1 | hypothetical protein | - |
HI799_RS09550 | 1970220..1970711 | + | 492 | WP_038961926.1 | glycoside hydrolase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1895924..1988943 | 93019 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 9834.30 Da Isoelectric Point: 8.7458
>T155518 WP_016721901.1 NZ_CP052116:c1965950-1965687 [Ralstonia solanacearum]
MKAKHKKTLDLIFSRPTPAGVKWNDLVGLLVELGAEITEREGSRVAVFLFNQVKVMHRPHPSPDVDKGAVASIRKWLEDN
ATEWNNE
MKAKHKKTLDLIFSRPTPAGVKWNDLVGLLVELGAEITEREGSRVAVFLFNQVKVMHRPHPSPDVDKGAVASIRKWLEDN
ATEWNNE
Download Length: 264 bp
>T155518 NZ_CP068805:2967113-2967220 [Escherichia coli]
ATGACGCTCACGCAGTTTGCCATGACTTTCTGGCACGACTTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCACGCAGTTTGCCATGACTTTCTGGCACGACTTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 113 a.a. Molecular weight: 12183.80 Da Isoelectric Point: 4.8946
>AT155518 WP_038961924.1 NZ_CP052116:c1965694-1965356 [Ralstonia solanacearum]
MNNVMIIGGEKAVISFDPELEMFRGEFIGLNGGADFYASDVAGLHREGELSLRTFMEECVRRGVEPRRSFSGKFVLRTSE
KTHEAAAIAAAAHGVSLNQWVSDVIEQAAIPA
MNNVMIIGGEKAVISFDPELEMFRGEFIGLNGGADFYASDVAGLHREGELSLRTFMEECVRRGVEPRRSFSGKFVLRTSE
KTHEAAAIAAAAHGVSLNQWVSDVIEQAAIPA
Download Length: 339 bp
>AT155518 NZ_CP068805:c2967065-2966999 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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