Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2947582..2947727 Replicon chromosome
Accession NZ_CP052036
Organism Klebsiella pneumoniae strain KPN41053

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2947618..2947720 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2947582..2947727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HH204_RS14000 2942712..2944772 + 2061 WP_004151449.1 oligopeptidase B -
HH204_RS14005 2944776..2945435 - 660 WP_002911407.1 exodeoxyribonuclease X -
HH204_RS14010 2945514..2945744 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HH204_RS14015 2945857..2946231 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HH204_RS14020 2946235..2947104 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HH204_RS14025 2947121..2947459 + 339 WP_002911404.1 YebY family protein -
- 2947582..2947727 - 146 - - Antitoxin
- 2947618..2947720 + 103 - - Toxin
HH204_RS14030 2948095..2948238 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HH204_RS14035 2948343..2949311 - 969 WP_074181864.1 VirK/YbjX family protein -
HH204_RS14040 2949468..2950121 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
HH204_RS14045 2950118..2950309 - 192 WP_002911395.1 YebW family protein -
HH204_RS14050 2950407..2950646 - 240 WP_002911393.1 YebV family protein -
HH204_RS14055 2950762..2952195 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T155406 NZ_CP052036:2947618-2947720 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT155406 NZ_CP052036:c2947727-2947582 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References